TY - GEN
T1 - Parkinson Disease Classification based on binary coded genetic algorithm and Extreme learning machine
AU - Sachnev, Vasily
AU - Kim, Hyoung Joong
PY - 2014
Y1 - 2014
N2 - In this paper, we propose a Binary Coded Genetic Algorithm combined with Extreme learning machine (BCGA-ELM) for Parkinson Disease classification problem. Proposed method analyses ParkDB data base of 22283 genes' expression information extracted from 22 normal patients and 50 Parkinson Disease patients. Proposed method can sufficiently recognize PD patients among normal persons using gene expression information. Besides, the proposed method can also find subset of genes which may be responsible for Parkinson Disease. Chosen subset of genes causes the maximum generalization performance for PD classification problem. Proposed BCGA-ELM also produces a robust solution. In our experiments we executed BCGA-ELM twice started from randomly generated initial data and found same solution at the end. Detected set of 19 genes was also verified by SVM and PBL-McRBFN. Both methods caused maximum generalization performance.
AB - In this paper, we propose a Binary Coded Genetic Algorithm combined with Extreme learning machine (BCGA-ELM) for Parkinson Disease classification problem. Proposed method analyses ParkDB data base of 22283 genes' expression information extracted from 22 normal patients and 50 Parkinson Disease patients. Proposed method can sufficiently recognize PD patients among normal persons using gene expression information. Besides, the proposed method can also find subset of genes which may be responsible for Parkinson Disease. Chosen subset of genes causes the maximum generalization performance for PD classification problem. Proposed BCGA-ELM also produces a robust solution. In our experiments we executed BCGA-ELM twice started from randomly generated initial data and found same solution at the end. Detected set of 19 genes was also verified by SVM and PBL-McRBFN. Both methods caused maximum generalization performance.
UR - http://www.scopus.com/inward/record.url?scp=84903721396&partnerID=8YFLogxK
U2 - 10.1109/ISSNIP.2014.6827649
DO - 10.1109/ISSNIP.2014.6827649
M3 - Conference contribution
AN - SCOPUS:84903721396
SN - 9781479928439
T3 - IEEE ISSNIP 2014 - 2014 IEEE 9th International Conference on Intelligent Sensors, Sensor Networks and Information Processing, Conference Proceedings
BT - IEEE ISSNIP 2014 - 2014 IEEE 9th International Conference on Intelligent Sensors, Sensor Networks and Information Processing, Conference Proceedings
PB - IEEE Computer Society
T2 - 9th IEEE International Conference on Intelligent Sensors, Sensor Networks and Information Processing, IEEE ISSNIP 2014
Y2 - 21 April 2014 through 24 April 2014
ER -