Pauson-Khand-type reaction mediated by RH(I) catalysts

Nakcheol Jeong; Byung Ki Sung; Jin Sung Kim; Soon Bong Park; Sung Deok Seo; Jin Young Shin; Kyu Yeol In; Yoon Kyung Choi

doi:10.1351/pac200274010085

Pauson-Khand-type reaction mediated by RH(I) catalysts

Nakcheol Jeong, Byung Ki Sung, Jin Sung Kim, Soon Bong Park, Sung Deok Seo, Jin Young Shin, Kyu Yeol In, Yoon Kyung Choi

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

Cocyclization of alkynes, alkenes, and carbon monoxide by transition metals (known as Pauson-Khand reaction when dicobalt octacarbonyl complexes are used) has been accepted as one of the most powerful tools in the synthesis of cyclopentenones. Despite significant progress in the various aspects of the reaction, we still needed new catalysts to expand the scope of the reaction further. We found rhodium (I) catalysts, e.g., RhCl(PPh₃)₃, trans-RhCl(CO)(PPh₃)₂, RhCl-(CO)(dppe), and trans-[RhCl(CO)(dppp)]₂, were also effective for this transformation. The scope and the efficiencies of the reaction could be tuned and expanded by the choice of catalysts. For example, we were able to devise an enantioselective PK-type reaction and a tandem strategy employing two catalysts in one pot. These results will be presented.

Original language	English
Pages (from-to)	85-91
Number of pages	7
Journal	Pure and Applied Chemistry
Volume	74
Issue number	1
DOIs	https://doi.org/10.1351/pac200274010085
Publication status	Published - 2002

Bibliographical note

Funding Information:
We gratefully acknowledge KOSEF for their generous financial support through CMDS.

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering

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title = "Pauson-Khand-type reaction mediated by RH(I) catalysts",

abstract = "Cocyclization of alkynes, alkenes, and carbon monoxide by transition metals (known as Pauson-Khand reaction when dicobalt octacarbonyl complexes are used) has been accepted as one of the most powerful tools in the synthesis of cyclopentenones. Despite significant progress in the various aspects of the reaction, we still needed new catalysts to expand the scope of the reaction further. We found rhodium (I) catalysts, e.g., RhCl(PPh3)3, trans-RhCl(CO)(PPh3)2, RhCl-(CO)(dppe), and trans-[RhCl(CO)(dppp)]2, were also effective for this transformation. The scope and the efficiencies of the reaction could be tuned and expanded by the choice of catalysts. For example, we were able to devise an enantioselective PK-type reaction and a tandem strategy employing two catalysts in one pot. These results will be presented.",

author = "Nakcheol Jeong and Sung, {Byung Ki} and Kim, {Jin Sung} and Park, {Soon Bong} and Seo, {Sung Deok} and Shin, {Jin Young} and In, {Kyu Yeol} and Choi, {Yoon Kyung}",

note = "Funding Information: We gratefully acknowledge KOSEF for their generous financial support through CMDS.",

year = "2002",

doi = "10.1351/pac200274010085",

language = "English",

volume = "74",

pages = "85--91",

journal = "Pure and Applied Chemistry",

issn = "0033-4545",

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T1 - Pauson-Khand-type reaction mediated by RH(I) catalysts

AU - Jeong, Nakcheol

AU - Sung, Byung Ki

AU - Kim, Jin Sung

AU - Park, Soon Bong

AU - Seo, Sung Deok

AU - Shin, Jin Young

AU - In, Kyu Yeol

AU - Choi, Yoon Kyung

N1 - Funding Information: We gratefully acknowledge KOSEF for their generous financial support through CMDS.

PY - 2002

Y1 - 2002

N2 - Cocyclization of alkynes, alkenes, and carbon monoxide by transition metals (known as Pauson-Khand reaction when dicobalt octacarbonyl complexes are used) has been accepted as one of the most powerful tools in the synthesis of cyclopentenones. Despite significant progress in the various aspects of the reaction, we still needed new catalysts to expand the scope of the reaction further. We found rhodium (I) catalysts, e.g., RhCl(PPh3)3, trans-RhCl(CO)(PPh3)2, RhCl-(CO)(dppe), and trans-[RhCl(CO)(dppp)]2, were also effective for this transformation. The scope and the efficiencies of the reaction could be tuned and expanded by the choice of catalysts. For example, we were able to devise an enantioselective PK-type reaction and a tandem strategy employing two catalysts in one pot. These results will be presented.

AB - Cocyclization of alkynes, alkenes, and carbon monoxide by transition metals (known as Pauson-Khand reaction when dicobalt octacarbonyl complexes are used) has been accepted as one of the most powerful tools in the synthesis of cyclopentenones. Despite significant progress in the various aspects of the reaction, we still needed new catalysts to expand the scope of the reaction further. We found rhodium (I) catalysts, e.g., RhCl(PPh3)3, trans-RhCl(CO)(PPh3)2, RhCl-(CO)(dppe), and trans-[RhCl(CO)(dppp)]2, were also effective for this transformation. The scope and the efficiencies of the reaction could be tuned and expanded by the choice of catalysts. For example, we were able to devise an enantioselective PK-type reaction and a tandem strategy employing two catalysts in one pot. These results will be presented.

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U2 - 10.1351/pac200274010085

DO - 10.1351/pac200274010085

M3 - Article

AN - SCOPUS:0036296010

SN - 0033-4545

VL - 74

SP - 85

EP - 91

JO - Pure and Applied Chemistry

JF - Pure and Applied Chemistry

IS - 1

ER -

Pauson-Khand-type reaction mediated by RH(I) catalysts

Abstract

Bibliographical note

ASJC Scopus subject areas

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