TY - JOUR
T1 - PE3-049 The Relationship between Internal Cardioversion Threshold or Post-Cardioversion Sinus Node Recovery Time and Atrial Structural or Autonomic Neural Remodeling in Persistent Atrial Fibrillation
AU - Park, Junbeom
AU - Won, Hoyoun
AU - Mun, Hee Sun
AU - Wee, Jin
AU - Shim, Jae Min
AU - Uhm, Jae Sun
AU - Hwang, Hye Jin
AU - Kim, Jong Youn
AU - Joung, Boyoung
AU - Lee, Moon Houng
AU - Pak, Hui Nam
PY - 2011
Y1 - 2011
N2 - Background: We hypothesized that cardioversion (CV) threshold and post-CV sinus node recovery time (PC-SNRT) are related with cardiac autonomic nerve function or atrial structural remodeling in persistent atrial fibrillation (PeAF). Methods: We included 74 patients with PeAF (62males, 54.8±10.5years old) who underwent radiofrequency catheter ablation (RFCA) and maintained sinus rhythm at the time of 3rd month Holter without taking any anti-arrhythmic drug or beta-blocker. At the beginning of RFCA, we delivered internal CV 2, 3, 5, 7, and 10J serially, and measured CV threshold and PC-SNRT. Results: 1. The patients with CHADS2 score>=1 showed higher CV threshold than those with 0 (8.3 ±2.1J vs. 6.2±2.5J, p=0.034). 2. CV threshold of the patients with left atrial(LA) volume>=120mL was significantly higher than those of patients with<120mL(8.2±2.2J vs. 6.4±2.7J, p=0.034). 3. PC-SNRT of the patients with LA-AP diameter (>=45mm) by echocardiography were significantly longer than that of the patients with<45mm (1422.2±1031.7ms vs. 1060.2±448.2ms, p=0.05). 4. PC-SNRT was correlated with 3rd month heart rate variability(HRV) including SDNN (R=0.400, p=0.005), HF (R=0.480, p=0.001), but not related with clinical recurrence of AF after RFCA. Conclusion: Both CV threshold and PC-SNRT were significantly greater in patients with atrial structural remodeling, but were not related with clinical outcome of RFCA in PeAF.
AB - Background: We hypothesized that cardioversion (CV) threshold and post-CV sinus node recovery time (PC-SNRT) are related with cardiac autonomic nerve function or atrial structural remodeling in persistent atrial fibrillation (PeAF). Methods: We included 74 patients with PeAF (62males, 54.8±10.5years old) who underwent radiofrequency catheter ablation (RFCA) and maintained sinus rhythm at the time of 3rd month Holter without taking any anti-arrhythmic drug or beta-blocker. At the beginning of RFCA, we delivered internal CV 2, 3, 5, 7, and 10J serially, and measured CV threshold and PC-SNRT. Results: 1. The patients with CHADS2 score>=1 showed higher CV threshold than those with 0 (8.3 ±2.1J vs. 6.2±2.5J, p=0.034). 2. CV threshold of the patients with left atrial(LA) volume>=120mL was significantly higher than those of patients with<120mL(8.2±2.2J vs. 6.4±2.7J, p=0.034). 3. PC-SNRT of the patients with LA-AP diameter (>=45mm) by echocardiography were significantly longer than that of the patients with<45mm (1422.2±1031.7ms vs. 1060.2±448.2ms, p=0.05). 4. PC-SNRT was correlated with 3rd month heart rate variability(HRV) including SDNN (R=0.400, p=0.005), HF (R=0.480, p=0.001), but not related with clinical recurrence of AF after RFCA. Conclusion: Both CV threshold and PC-SNRT were significantly greater in patients with atrial structural remodeling, but were not related with clinical outcome of RFCA in PeAF.
KW - cardioversion
KW - persistent atrial fibrillation
KW - sinus recovery time
UR - http://www.scopus.com/inward/record.url?scp=85008731460&partnerID=8YFLogxK
U2 - 10.4020/jhrs.27.PE3_049
DO - 10.4020/jhrs.27.PE3_049
M3 - Article
AN - SCOPUS:85008731460
SN - 1880-4276
VL - 27
SP - 386
JO - journal of arrhythmia
JF - journal of arrhythmia
ER -