Penalized geodesic tractography for mitigating gyral bias

Ye Wu; Yuanjing Feng; Dinggang Shen; Pew Thian Yap

doi:10.1007/978-3-030-00931-1_2

Penalized geodesic tractography for mitigating gyral bias

Ye Wu, Yuanjing Feng, Dinggang Shen, Pew Thian Yap

Department of Brain and Cognitive Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

5 Citations (Scopus)

Abstract

In this paper, we introduce a penalized geodesic tractography (PGT) algorithm for mitigating gyral bias in cortical tractography, which is essential for improving cortical connectomics. Unlike deterministic and probabilistic tractography algorithms that perform one-way tracking, PGT solves a global optimization problem in estimating the pathways connecting multiple regions, instead of local step-by-step orientation tracing. PGT is unconfounded by local false-positive or false-negative fiber orientations and ensures that fiber streamlines that are intended to connect two regions do not terminate prematurely. We show that PGT reduces gyral bias by allowing streamlines to make sharper turns into the cortical gyral matter and results in a significantly more uniform spatial distribution of cortical connections.

Original language	English
Title of host publication	Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings
Editors	Alejandro F. Frangi, Christos Davatzikos, Gabor Fichtinger, Carlos Alberola-López, Julia A. Schnabel
Publisher	Springer Verlag
Pages	12-19
Number of pages	8
ISBN (Print)	9783030009304
DOIs	https://doi.org/10.1007/978-3-030-00931-1_2
Publication status	Published - 2018
Event	21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018 - Granada, Spain Duration: 2018 Sept 16 → 2018 Sept 20

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume	11072 LNCS
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Other

Other	21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018
Country/Territory	Spain
City	Granada
Period	18/9/16 → 18/9/20

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2018.

ASJC Scopus subject areas

Theoretical Computer Science
General Computer Science

Access to Document

10.1007/978-3-030-00931-1_2

Cite this

Wu, Y., Feng, Y., Shen, D., & Yap, P. T. (2018). Penalized geodesic tractography for mitigating gyral bias. In A. F. Frangi, C. Davatzikos, G. Fichtinger, C. Alberola-López, & J. A. Schnabel (Eds.), Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings (pp. 12-19). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 11072 LNCS). Springer Verlag. https://doi.org/10.1007/978-3-030-00931-1_2

Penalized geodesic tractography for mitigating gyral bias. / Wu, Ye; Feng, Yuanjing; Shen, Dinggang et al.
Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. ed. / Alejandro F. Frangi; Christos Davatzikos; Gabor Fichtinger; Carlos Alberola-López; Julia A. Schnabel. Springer Verlag, 2018. p. 12-19 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 11072 LNCS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Wu, Y, Feng, Y, Shen, D & Yap, PT 2018, Penalized geodesic tractography for mitigating gyral bias. in AF Frangi, C Davatzikos, G Fichtinger, C Alberola-López & JA Schnabel (eds), Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 11072 LNCS, Springer Verlag, pp. 12-19, 21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018, Granada, Spain, 18/9/16. https://doi.org/10.1007/978-3-030-00931-1_2

Wu Y, Feng Y, Shen D, Yap PT. Penalized geodesic tractography for mitigating gyral bias. In Frangi AF, Davatzikos C, Fichtinger G, Alberola-López C, Schnabel JA, editors, Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. Springer Verlag. 2018. p. 12-19. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). doi: 10.1007/978-3-030-00931-1_2

Wu, Ye ; Feng, Yuanjing ; Shen, Dinggang et al. / Penalized geodesic tractography for mitigating gyral bias. Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. editor / Alejandro F. Frangi ; Christos Davatzikos ; Gabor Fichtinger ; Carlos Alberola-López ; Julia A. Schnabel. Springer Verlag, 2018. pp. 12-19 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).

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Penalized geodesic tractography for mitigating gyral bias

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