Abstract
A nanomechanical microcantilever promises to bring about revolution in the field of chemical and biological analysis system development. We report the peptide immobilized nanomechanical microcantilever operated in dynamic vibration mode for quantitative label-free detection of protein kinase A. The detection principle of dynamic cantilever is that specific interaction on the microcantilever surface lead to the dynamic response change of microcantilevers. We achieved the protein kinase A detection in the low concentration as much as 6.6 pM through measuring the dynamic response change of microcantilever.
| Original language | English |
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| Title of host publication | Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Publisher | Japan Academic Association Inc |
| Pages | 768-770 |
| Number of pages | 3 |
| Publication status | Published - 2006 Jan 1 |
| Event | 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan Duration: 2006 Nov 5 → 2006 Nov 9 |
Other
| Other | 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 |
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| Country/Territory | Japan |
| City | Tokyo |
| Period | 06/11/5 → 06/11/9 |
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering