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Phosphorylation of nicastrin by SGK1 leads to its degradation through lysosomal and proteasomal pathways
Jung Soon Mo
, Ji Hye Yoon
, Ji Ae Hong
, Mi Yeon Kim
, Eun Jung Ann
, Ji Seon Ahn
, Su Man Kim
, Hyeong Jin Baek
, Florian Lang
,
Eui Ju Choi
, Hee Sae Park
*
*
Corresponding author for this work
Department of Life Sciences
Research output
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Contribution to journal
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Article
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peer-review
15
Citations (Scopus)
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Keyphrases
Phosphorylation
100%
Protein Kinase
100%
Endolysosomal System
100%
Glucocorticoid-induced
100%
Nicastrin
100%
Proteasomal Pathway
100%
γ-secretase
57%
Protein Level
14%
Amyloid Precursor Protein
14%
Proteolysis
14%
Protein Stability
14%
Protein Degradation
14%
Kinase Activity
14%
Intramembranous
14%
γ-Secretase Activity
14%
Notch Receptors
14%
Biochemistry, Genetics and Molecular Biology
Protein Kinases
100%
Nicastrin
100%
Glucocorticoid
100%
Gamma Secretase
71%
Protein Catabolism
28%
Kinase
14%
Phosphotransferase
14%
Amyloid Precursor Protein
14%
Protein Stability
14%
Notch Proteins
14%