Abstract
Ultraviolet B (UVB) irradiation may induce the acceleration of skin aging. The purpose of this study was to develop an effective formulation containing tannase-converted green tea extract (FTGE) to inhibit UVB-induced oxidative damage. Significant (p∈<∈0.05) prevention of the reduced form of glutathione (GSH) depletion was observed in mice treated with FTGE. The hydrogen peroxide levels of mice treated with FTGE were similar to those of UVB non-irradiated mice. No significant difference was observed between No UVB control and FTGE mice. Also, mice treated with FTGE had significant (p∈<∈0.05) decreases in thiobarbituric acid-reactive substance levels by lipid peroxidation compared with No UVB control mice. Our data suggest that this formulation may be effective in protecting skin from UVB photodamage.
Original language | English |
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Pages (from-to) | 165-175 |
Number of pages | 11 |
Journal | Applied Biochemistry and Biotechnology |
Volume | 166 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2012 Jan |
Bibliographical note
Funding Information:Acknowledgment This research was supported by the Technology Development Program for Food, Ministry for Food, Agriculture, Forestry, and Fisheries, Republic of Korea.
Keywords
- Formulation
- Green tea
- Oxidative stress
- Photoprotection
- Tannase
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology