Physical characterization of ultrashort laser pulse drilling of biological tissue

M. D. Feit, A. M. Rubenchik, B. M. Kim, L. B. Da Silva, M. D. Perry

Research output: Contribution to journalArticlepeer-review

51 Citations (Scopus)


Ultrashort laser pulse ablation removes material with low-energy fluence required and minimal collateral damage. The ultimate usefulness of this technology for biomedical application depends, in part, on characterization of the physical conditions attained, and determination of the zone of shockwave and heat-affected material in particular tissues. Detailed numerical modeling of the relevant physics (deposition, plasma formation, shockwave generation and propagation, thermal conduction) are providing this information. A wide range of time scales is involved, ranging from picosecond for energy deposition and peak pressure and temperature, to nanosecond for development of shockwave, to microsecond for macroscopic thermophysical response.

Original languageEnglish
Pages (from-to)869-874
Number of pages6
JournalApplied Surface Science
Publication statusPublished - 1998 May
Externally publishedYes

Bibliographical note

Funding Information:
This work was performed at Lawrence Livermore National Laboratory under the auspices of the US Department of Energy under Contract No. W-7405-ENG-48.


  • Biological tissue
  • Physical characterization
  • Ultrashort laser pulse ablation

ASJC Scopus subject areas

  • General Chemistry
  • Condensed Matter Physics
  • General Physics and Astronomy
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films


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