Physical comorbidities in older adults receiving antidepressants in Asia

Xiao Mei Zhong; Min Dong; Fei Wang; Qinge Zhang; Gabor S. Ungvari; Chee H. Ng; Helen F.K. Chiu; Tian Mei Si; Kang Sim; Ajit Avasthi; Sandeep Grover; Mian Yoon Chong; Kok Yoon Chee; Shigenobu Kanba; Min-Soo Lee; Shu Yu Yang; Pichet Udomratn; Roy A. Kallivayalil; Andi J. Tanra; Margarita M. Maramis; Winston W. Shen; Norman Sartorius; Rathi Mahendran; Chay Hoon Tan; Naotaka Shinfuku; Yu Tao Xiang

doi:10.1111/psyg.12327

Physical comorbidities in older adults receiving antidepressants in Asia

Xiao Mei Zhong, Min Dong, Fei Wang, Qinge Zhang, Gabor S. Ungvari, Chee H. Ng, Helen F.K. Chiu, Tian Mei Si, Kang Sim, Ajit Avasthi, Sandeep Grover, Mian Yoon Chong, Kok Yoon Chee, Shigenobu Kanba, Min-Soo Lee, Shu Yu Yang, Pichet Udomratn, Roy A. Kallivayalil, Andi J. Tanra, Margarita M. MaramisWinston W. Shen, Norman Sartorius, Rathi Mahendran, Chay Hoon Tan, Naotaka Shinfuku, Yu Tao Xiang

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Background: The present study explored the patterns of physical comorbidities and their associated demographic and clinical factors in older psychiatric patients prescribed with antidepressants in Asia. Methods: Demographic and clinical information of 955 older adults were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Standardized data collection procedure was used to record demographic and clinical data. Results: Proportion of physical comorbidities in this cohort was 44%. Multiple logistic regression analyses showed that older age (OR = 1.7, P < 0.001), higher number of depressive symptoms (OR = 1.09, P = 0.016), being treated in psychiatric hospital (OR = 0.5, P = 0.002), living in high income countries/territories (OR = 2.4, P = 0.002), use of benzodiazepines (OR = 1.4, P = 0.013) and diagnosis of ‘other psychiatric disorders’ (except mood, anxiety disorders and schizophrenia) (OR = 2.7, P < 0.001) were significantly associated with physical comorbidities. Conclusions: Physical comorbidities in older patients prescribed with antidepressants were common in Asia. Integrating physical care into the treatment of older psychiatric patients should be urgently considered.

Original language	English
Pages (from-to)	351-356
Number of pages	6
Journal	Psychogeriatrics
Volume	18
Issue number	5
DOIs	https://doi.org/10.1111/psyg.12327
Publication status	Published - 2018 Sept 1

Keywords

antidepressant
Asia
older adults
physical comorbidity

ASJC Scopus subject areas

Gerontology
Geriatrics and Gerontology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/psyg.12327

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Zhong, X. M., Dong, M., Wang, F., Zhang, Q., Ungvari, G. S., Ng, C. H., Chiu, H. F. K., Si, T. M., Sim, K., Avasthi, A., Grover, S., Chong, M. Y., Chee, K. Y., Kanba, S., Lee, M.-S., Yang, S. Y., Udomratn, P., Kallivayalil, R. A., Tanra, A. J., ... Xiang, Y. T. (2018). Physical comorbidities in older adults receiving antidepressants in Asia. Psychogeriatrics, 18(5), 351-356. https://doi.org/10.1111/psyg.12327

Zhong, XM, Dong, M, Wang, F, Zhang, Q, Ungvari, GS, Ng, CH, Chiu, HFK, Si, TM, Sim, K, Avasthi, A, Grover, S, Chong, MY, Chee, KY, Kanba, S, Lee, M-S, Yang, SY, Udomratn, P, Kallivayalil, RA, Tanra, AJ, Maramis, MM, Shen, WW, Sartorius, N, Mahendran, R, Tan, CH, Shinfuku, N & Xiang, YT 2018, 'Physical comorbidities in older adults receiving antidepressants in Asia', Psychogeriatrics, vol. 18, no. 5, pp. 351-356. https://doi.org/10.1111/psyg.12327

@article{19bce83e2f7c484aac822f87402f6a27,

title = "Physical comorbidities in older adults receiving antidepressants in Asia",

abstract = "Background: The present study explored the patterns of physical comorbidities and their associated demographic and clinical factors in older psychiatric patients prescribed with antidepressants in Asia. Methods: Demographic and clinical information of 955 older adults were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Standardized data collection procedure was used to record demographic and clinical data. Results: Proportion of physical comorbidities in this cohort was 44%. Multiple logistic regression analyses showed that older age (OR = 1.7, P < 0.001), higher number of depressive symptoms (OR = 1.09, P = 0.016), being treated in psychiatric hospital (OR = 0.5, P = 0.002), living in high income countries/territories (OR = 2.4, P = 0.002), use of benzodiazepines (OR = 1.4, P = 0.013) and diagnosis of {\textquoteleft}other psychiatric disorders{\textquoteright} (except mood, anxiety disorders and schizophrenia) (OR = 2.7, P < 0.001) were significantly associated with physical comorbidities. Conclusions: Physical comorbidities in older patients prescribed with antidepressants were common in Asia. Integrating physical care into the treatment of older psychiatric patients should be urgently considered.",

keywords = "antidepressant, Asia, older adults, physical comorbidity",

author = "Zhong, {Xiao Mei} and Min Dong and Fei Wang and Qinge Zhang and Ungvari, {Gabor S.} and Ng, {Chee H.} and Chiu, {Helen F.K.} and Si, {Tian Mei} and Kang Sim and Ajit Avasthi and Sandeep Grover and Chong, {Mian Yoon} and Chee, {Kok Yoon} and Shigenobu Kanba and Min-Soo Lee and Yang, {Shu Yu} and Pichet Udomratn and Kallivayalil, {Roy A.} and Tanra, {Andi J.} and Maramis, {Margarita M.} and Shen, {Winston W.} and Norman Sartorius and Rathi Mahendran and Tan, {Chay Hoon} and Naotaka Shinfuku and Xiang, {Yu Tao}",

year = "2018",

month = sep,

day = "1",

doi = "10.1111/psyg.12327",

language = "English",

volume = "18",

pages = "351--356",

journal = "Psychogeriatrics",

issn = "1346-3500",

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TY - JOUR

T1 - Physical comorbidities in older adults receiving antidepressants in Asia

AU - Zhong, Xiao Mei

AU - Dong, Min

AU - Wang, Fei

AU - Zhang, Qinge

AU - Ungvari, Gabor S.

AU - Ng, Chee H.

AU - Chiu, Helen F.K.

AU - Si, Tian Mei

AU - Sim, Kang

AU - Avasthi, Ajit

AU - Grover, Sandeep

AU - Chong, Mian Yoon

AU - Chee, Kok Yoon

AU - Kanba, Shigenobu

AU - Lee, Min-Soo

AU - Yang, Shu Yu

AU - Udomratn, Pichet

AU - Kallivayalil, Roy A.

AU - Tanra, Andi J.

AU - Maramis, Margarita M.

AU - Shen, Winston W.

AU - Sartorius, Norman

AU - Mahendran, Rathi

AU - Tan, Chay Hoon

AU - Shinfuku, Naotaka

AU - Xiang, Yu Tao

PY - 2018/9/1

Y1 - 2018/9/1

N2 - Background: The present study explored the patterns of physical comorbidities and their associated demographic and clinical factors in older psychiatric patients prescribed with antidepressants in Asia. Methods: Demographic and clinical information of 955 older adults were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Standardized data collection procedure was used to record demographic and clinical data. Results: Proportion of physical comorbidities in this cohort was 44%. Multiple logistic regression analyses showed that older age (OR = 1.7, P < 0.001), higher number of depressive symptoms (OR = 1.09, P = 0.016), being treated in psychiatric hospital (OR = 0.5, P = 0.002), living in high income countries/territories (OR = 2.4, P = 0.002), use of benzodiazepines (OR = 1.4, P = 0.013) and diagnosis of ‘other psychiatric disorders’ (except mood, anxiety disorders and schizophrenia) (OR = 2.7, P < 0.001) were significantly associated with physical comorbidities. Conclusions: Physical comorbidities in older patients prescribed with antidepressants were common in Asia. Integrating physical care into the treatment of older psychiatric patients should be urgently considered.

AB - Background: The present study explored the patterns of physical comorbidities and their associated demographic and clinical factors in older psychiatric patients prescribed with antidepressants in Asia. Methods: Demographic and clinical information of 955 older adults were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Standardized data collection procedure was used to record demographic and clinical data. Results: Proportion of physical comorbidities in this cohort was 44%. Multiple logistic regression analyses showed that older age (OR = 1.7, P < 0.001), higher number of depressive symptoms (OR = 1.09, P = 0.016), being treated in psychiatric hospital (OR = 0.5, P = 0.002), living in high income countries/territories (OR = 2.4, P = 0.002), use of benzodiazepines (OR = 1.4, P = 0.013) and diagnosis of ‘other psychiatric disorders’ (except mood, anxiety disorders and schizophrenia) (OR = 2.7, P < 0.001) were significantly associated with physical comorbidities. Conclusions: Physical comorbidities in older patients prescribed with antidepressants were common in Asia. Integrating physical care into the treatment of older psychiatric patients should be urgently considered.

KW - antidepressant

KW - Asia

KW - older adults

KW - physical comorbidity

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DO - 10.1111/psyg.12327

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C2 - 29989257

AN - SCOPUS:85050463847

SN - 1346-3500

VL - 18

SP - 351

EP - 356

JO - Psychogeriatrics

JF - Psychogeriatrics

IS - 5

ER -

Physical comorbidities in older adults receiving antidepressants in Asia

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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