Pinolenic Acid in Structured Triacylglycerols Exhibits Superior Intestinal Lymphatic Absorption As Compared to Pinolenic Acid in Natural Pine Nut Oil

Min Yu Chung; Hyunjoon Woo; Juyeon Kim; Daecheol Kong; Hee Don Choi; In Wook Choi; In Hwan Kim; Sang K. Noh; Byung Hee Kim

doi:10.1021/acs.jafc.6b05216

Pinolenic Acid in Structured Triacylglycerols Exhibits Superior Intestinal Lymphatic Absorption As Compared to Pinolenic Acid in Natural Pine Nut Oil

Min Yu Chung, Hyunjoon Woo, Juyeon Kim, Daecheol Kong, Hee Don Choi, In Wook Choi, In Hwan Kim, Sang K. Noh, Byung Hee Kim

Department of Public Health Sciences

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The positional distribution pattern of fatty acids (FAs) in the triacylglycerols (TAGs) affects intestinal absorption of these FAs. The aim of this study was to compare lymphatic absorption of pinolenic acid (PLA) present in structured pinolenic TAG (SPT) where PLA was evenly distributed on the glycerol backbone, with absorption of pine nut oil (PNO) where PLA was predominantly positioned at the sn-3 position. SPT was prepared via the nonspecific lipase-catalyzed esterification of glycerol with free FA obtained from PNO. Lymphatic absorption of PLA from PNO and from SPT was compared in a rat model of lymphatic cannulation. Significantly (P < 0.05) greater amounts of PLA were detected in lymph collected for 8 h from an emulsion containing SPT (28.5 ± 0.7% dose) than from an emulsion containing PNO (26.2 ± 0.6% dose), thereby indicating that PLA present in SPT has a greater capacity for lymphatic absorption than PLA from PNO.

Original language	English
Pages (from-to)	1543-1549
Number of pages	7
Journal	Journal of agricultural and food chemistry
Volume	65
Issue number	8
DOIs	https://doi.org/10.1021/acs.jafc.6b05216
Publication status	Published - 2017 Mar 1

Keywords

Novozym 435
lymphatic absorption
pinolenic acid
stereospecific numbering position
structured triacylglycerols

ASJC Scopus subject areas

Chemistry(all)
Agricultural and Biological Sciences(all)

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10.1021/acs.jafc.6b05216

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title = "Pinolenic Acid in Structured Triacylglycerols Exhibits Superior Intestinal Lymphatic Absorption As Compared to Pinolenic Acid in Natural Pine Nut Oil",

abstract = "The positional distribution pattern of fatty acids (FAs) in the triacylglycerols (TAGs) affects intestinal absorption of these FAs. The aim of this study was to compare lymphatic absorption of pinolenic acid (PLA) present in structured pinolenic TAG (SPT) where PLA was evenly distributed on the glycerol backbone, with absorption of pine nut oil (PNO) where PLA was predominantly positioned at the sn-3 position. SPT was prepared via the nonspecific lipase-catalyzed esterification of glycerol with free FA obtained from PNO. Lymphatic absorption of PLA from PNO and from SPT was compared in a rat model of lymphatic cannulation. Significantly (P < 0.05) greater amounts of PLA were detected in lymph collected for 8 h from an emulsion containing SPT (28.5 ± 0.7% dose) than from an emulsion containing PNO (26.2 ± 0.6% dose), thereby indicating that PLA present in SPT has a greater capacity for lymphatic absorption than PLA from PNO.",

keywords = "Novozym 435, lymphatic absorption, pinolenic acid, stereospecific numbering position, structured triacylglycerols",

author = "Chung, {Min Yu} and Hyunjoon Woo and Juyeon Kim and Daecheol Kong and Choi, {Hee Don} and Choi, {In Wook} and Kim, {In Hwan} and Noh, {Sang K.} and Kim, {Byung Hee}",

note = "Funding Information: This research was supported by the Main Research Program (E0124200-03) of the Korea Food Research Institute (KFRI) funded by the Ministry of Science ICT & Future Planning, and was also supported by the Sookmyung Women's University Research Grants (1-1603-2008). Publisher Copyright: {\textcopyright} 2017 American Chemical Society.",

year = "2017",

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doi = "10.1021/acs.jafc.6b05216",

language = "English",

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journal = "Journal of Agricultural and Food Chemistry",

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T1 - Pinolenic Acid in Structured Triacylglycerols Exhibits Superior Intestinal Lymphatic Absorption As Compared to Pinolenic Acid in Natural Pine Nut Oil

AU - Chung, Min Yu

AU - Woo, Hyunjoon

AU - Kim, Juyeon

AU - Kong, Daecheol

AU - Choi, Hee Don

AU - Choi, In Wook

AU - Kim, In Hwan

AU - Noh, Sang K.

AU - Kim, Byung Hee

N1 - Funding Information: This research was supported by the Main Research Program (E0124200-03) of the Korea Food Research Institute (KFRI) funded by the Ministry of Science ICT & Future Planning, and was also supported by the Sookmyung Women's University Research Grants (1-1603-2008). Publisher Copyright: © 2017 American Chemical Society.

PY - 2017/3/1

Y1 - 2017/3/1

N2 - The positional distribution pattern of fatty acids (FAs) in the triacylglycerols (TAGs) affects intestinal absorption of these FAs. The aim of this study was to compare lymphatic absorption of pinolenic acid (PLA) present in structured pinolenic TAG (SPT) where PLA was evenly distributed on the glycerol backbone, with absorption of pine nut oil (PNO) where PLA was predominantly positioned at the sn-3 position. SPT was prepared via the nonspecific lipase-catalyzed esterification of glycerol with free FA obtained from PNO. Lymphatic absorption of PLA from PNO and from SPT was compared in a rat model of lymphatic cannulation. Significantly (P < 0.05) greater amounts of PLA were detected in lymph collected for 8 h from an emulsion containing SPT (28.5 ± 0.7% dose) than from an emulsion containing PNO (26.2 ± 0.6% dose), thereby indicating that PLA present in SPT has a greater capacity for lymphatic absorption than PLA from PNO.

AB - The positional distribution pattern of fatty acids (FAs) in the triacylglycerols (TAGs) affects intestinal absorption of these FAs. The aim of this study was to compare lymphatic absorption of pinolenic acid (PLA) present in structured pinolenic TAG (SPT) where PLA was evenly distributed on the glycerol backbone, with absorption of pine nut oil (PNO) where PLA was predominantly positioned at the sn-3 position. SPT was prepared via the nonspecific lipase-catalyzed esterification of glycerol with free FA obtained from PNO. Lymphatic absorption of PLA from PNO and from SPT was compared in a rat model of lymphatic cannulation. Significantly (P < 0.05) greater amounts of PLA were detected in lymph collected for 8 h from an emulsion containing SPT (28.5 ± 0.7% dose) than from an emulsion containing PNO (26.2 ± 0.6% dose), thereby indicating that PLA present in SPT has a greater capacity for lymphatic absorption than PLA from PNO.

KW - Novozym 435

KW - lymphatic absorption

KW - pinolenic acid

KW - stereospecific numbering position

KW - structured triacylglycerols

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Pinolenic Acid in Structured Triacylglycerols Exhibits Superior Intestinal Lymphatic Absorption As Compared to Pinolenic Acid in Natural Pine Nut Oil

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