Polymer-coated spherical mesoporous silica for pH-controlled delivery of insulin

Sae Rom Choi, Dong Jin Jang, Sanghyun Kim, Sunhyung An, Jinwoo Lee, Euichaul Oh, Jungbae Kim

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)


We report a pH-controlled insulin release system to provide an oral administration route. Mesoporous silica was chosen as a drug carrier, and pH-sensitive polymers were coated onto spherical mesocellular foam with pre-adsorbed insulin. We evaluated the insulin release in both acidic and neutral solutions to compare how this system behaves under different pH conditions.

Original languageEnglish
Pages (from-to)616-619
Number of pages4
JournalJournal of Materials Chemistry B
Issue number6
Publication statusPublished - 2014 Feb 14

ASJC Scopus subject areas

  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)


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