Porous TiO2 films on Ti implants for controlled release of tetracycline-hydrochloride (TCH)

Cheol Min Han, Eun Jung Lee, Hyoun Ee Kim, Young Hag Koh, Jun Hyeog Jang

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)


Micro- and nano-porous TiO2 films were created on the surface of Ti implants using micro-arc oxidation and anodic titanium oxide treatments, respectively, to load a sol-gel derived silica xerogel for the controlled release of the antibiotic drug, tetracycline-hydrochloride (TCH). When the silica xerogel containing TCH was loaded into porous TiO2 films, a very high drug loading efficiency was observed compared to when it was loaded in Ti implants without a TiO2 film. Moreover, TCH was released in a controlled manner for up to 7 days.

Original languageEnglish
Pages (from-to)8074-8076
Number of pages3
JournalThin Solid Films
Issue number22
Publication statusPublished - 2011 Sept 1

Bibliographical note

Funding Information:
This research was supported by WCU (World Class University) project through National Research Foundation of Korea funded by the Ministry of Education, Science and Technology ( R31-2008-000-10075-0 ) and by the Fundamental R&D Program for Core Technology of Materials funded by the Ministry of Knowledge Economy, Republic of Korea .


  • Anodic titanium oxide
  • Controlled drug release
  • Micro-arc oxidation
  • Silica xerogel

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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