@article{f69be01f5edc47ff88c1952c500a8026,
title = "Post-polymerization modification reactions of poly(glycidyl methacrylate)s",
abstract = "Post-polymerisation modification of poly(glycidyl methacrylate) (PGMA) through the nucleophilic ring opening reactions of the pendent epoxide groups allows for the installation of a variety of functionalities onto the reactive scaffold. The primary modification processes involve amine-epoxy, thiol-epoxy, azide-epoxy, acid-epoxy, and hydrolysis reactions. In all cases, sequential post-synthesis modification reactions can also be carried out if multiply-functionalised polymers are required. This, in particular, includes reactions of the hydroxyl group(s) that come into being through the initial oxirane ring-opening reaction. The overall flexibility of these functionalisations, coupled with the commercial availability of glycidyl methacrylate monomer, its controlled polymerisation behaviour through free radical polymerisation methods and high shelf life of the resulting polymers makes PGMA one of the most adaptable reactive scaffolds in polymer chemistry. In this review article, our aim is to discuss the fundamental aspects of the epoxy ring-opening reactions and highlight the utilitarian nature of PGMA by addressing the range of chemistry that has been used to transform this simple structure into a plethora of customised functional polymers.",
author = "Muzammil, {Ezzah M.} and Anzar Khan and Stuparu, {Mihaiela C.}",
note = "Funding Information: Born in Romania, Mihaiela received her Master degree in Organic Chemistry from the Babes-Bolyai University, Roma- nia, under the guidance of Prof. I. Grosu. She then moved to Freie Universit{\"a}t Berlin, Germany, and nally to ETH-Z{\"u}rich, Switzer- land, to obtain her doctoral degree in the group of Prof. A. D. Schl{\"u}ter. Aer a one-year post- doctoral stay in the group of Prof. H. K. Hall Jr at the University of Arizona at Tucson (USA), Mihaiela returned to Z{\"u}rich as a member of the Prof. J. Siegel's group at the University of Z{\"u}rich. In 2009, Mihaiela received the Ambizione fellowship from the Swiss National Science Foundation. Under the mentorship of Prof. Siegel, Mihaiela's research efforts at the University of Z{\"u}rich were directed towards creating a research program focused on introducing the corannulene chemistry to the macromolecular science. The University of Z{\"u}rich recognized Mihaiela's research efforts in this direction by bestowing upon her the title of {\textquoteleft}Privat-Dozent{\textquoteright}. Since 2014, Mihaiela is a Nanyang Assistant Professor at NTU Singapore. Here, her group is investigating utility of the corannulene motif for the preparation of functional so materials. Funding Information: EMM and MCS are thankful for nancial support from NTU Singapore (M4081566). This work was by National Research Foundation of Korea grant funded by the Korea government (MSIP) (NRF-2015R1D1A1A01057796). Publisher Copyright: {\textcopyright} 2017 The Royal Society of Chemistry.",
year = "2017",
doi = "10.1039/c7ra11093f",
language = "English",
volume = "7",
pages = "55874--55884",
journal = "RSC Advances",
issn = "2046-2069",
publisher = "Royal Society of Chemistry",
number = "88",
}