Abstract
Strain NK34 was characterized for probiotic use. Strain NK34 was named Lactococcus lactis NK34 based on API 50 CHL kit results and 16S rDNA sequencing. L lactis NK34 was highly resistant to artificial gastric juice (pH 2.5) and artificial bile acid. Based on results from the API ZYM kit, 4 enzymes were produced. L. lactis NK34 was resistant to all antibiotics tested except for 10 μg/mL roxithromycin and 10 μg/mL erythromycin. The cholesterol-lowering effect of L. lactis NK34 was about 46.9%. Concentrations of interleukin (IL)-1α in the 20× concentrated supernatant of L. lactis NK34 was about 361 pg/mL. L. lactis NK34 was also found to inhibit the growth of colon cancer cells due to MNNG-induced DNA damage. These results demonstrate the potential of L. lactis NK34 as a health-promoting probiotic.
Original language | English |
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Pages (from-to) | 843-847 |
Number of pages | 5 |
Journal | Food Science and Biotechnology |
Volume | 16 |
Issue number | 5 |
Publication status | Published - 2007 |
Keywords
- Cholesterol-lowering activity
- DNA damage
- Immunolstimulating activity
- Jeotgal
- Lactococcus lactis
- Probiotics
ASJC Scopus subject areas
- Biotechnology
- Food Science
- Applied Microbiology and Biotechnology