Precision medicine for psychopharmacology: a general introduction

Cheolmin Shin, Changsu Han, Chi Un Pae, Ashwin A. Patkar

    Research output: Contribution to journalReview articlepeer-review

    15 Citations (Scopus)

    Abstract

    Introduction: Precision medicine is an emerging medical model that can provide accurate diagnoses and tailored therapeutic strategies for patients based on data pertaining to genes, microbiomes, environment, family history and lifestyle. Areas covered: Here, we provide basic information about precision medicine and newly introduced concepts, such as the precision medicine ecosystem and big data processing, and omics technologies including pharmacogenomics, pharamacometabolomics, pharmacoproteomics, pharmacoepigenomics, connectomics and exposomics. The authors review the current state of omics in psychiatry and the future direction of psychopharmacology as it moves towards precision medicine. Expert commentary: Advances in precision medicine have been facilitated by achievements in multiple fields, including large-scale biological databases, powerful methods for characterizing patients (such as genomics, proteomics, metabolomics, diverse cellular assays, and even social networks and mobile health technologies), and computer-based tools for analyzing large amounts of data.

    Original languageEnglish
    Pages (from-to)831-839
    Number of pages9
    JournalExpert Review of Neurotherapeutics
    Volume16
    Issue number7
    DOIs
    Publication statusPublished - 2016 Jul 2

    Bibliographical note

    Publisher Copyright:
    © 2016 Informa UK Limited, trading as Taylor & Francis Group.

    Keywords

    • Precision medicine
    • big data
    • connectomics
    • electronic health record
    • electronic medical record
    • exposomics
    • personalized medicine
    • pharmacogenomics
    • pharmacometabolomics
    • psychopharmacology

    ASJC Scopus subject areas

    • General Neuroscience
    • Clinical Neurology
    • Pharmacology (medical)

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