Prediction of liver cirrhosis, using diagnostic imaging tools

Suk Keu Yeom, Chang Hee Lee, Sang Hoon Cha, Cheol Min Park

Research output: Contribution to journalReview articlepeer-review

90 Citations (Scopus)


Early diagnosis of liver cirrhosis is important. Ultrasoundguided liver biopsy is the gold standard for diagnosis of liver cirrhosis. However, its invasiveness and sampling bias limit the applicability of the method. Basic imaging for the diagnosis of liver cirrhosis has developed over the last few decades, enabling early detection of morphological changes of the liver by ultrasonography (US), computed tomography, and magnetic resonance imaging (MRI). They are also accurate diagnostic methods for advanced liver cirrhosis, for which early diagnosis is difficult. There are a number of ways to compensate for this difficulty, including texture analysis to more closely identify the homogeneity of hepatic parenchyma, elastography to measure the stiffness and elasticity of the liver, and perfusion studies to determine the blood flow volume, transit time, and velocity. Amongst these methods, elastography using US and MRI was found to be slightly easier, faster, and able to provide an accurate diagnosis. Early diagnosis of liver cirrhosis using MRI or US elastography is therefore a realistic alternative, but further research is still needed.

Original languageEnglish
Pages (from-to)2069-2079
Number of pages11
JournalWorld Journal of Hepatology
Issue number17
Publication statusPublished - 2015
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s) 2015.


  • Acoustic radiation force impulse imaging
  • Computed tomography
  • Liver fibrosis
  • Magnetic resonance elastography
  • Magnetic resonance imaging
  • Sonoelastography
  • Ultrasonography

ASJC Scopus subject areas

  • Hepatology


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