Predictive models of objective oropharyngeal OSA surgery outcomes: Success rate and AHI reduction ratio

Ji Ho Choi; Jae Yong Lee; Jaehyung Cha; Kangwoo Kim; Seung No Hong; Seung Hoon Lee

doi:10.1371/journal.pone.0185201

Predictive models of objective oropharyngeal OSA surgery outcomes: Success rate and AHI reduction ratio

Ji Ho Choi, Jae Yong Lee, Jaehyung Cha, Kangwoo Kim, Seung No Hong, Seung Hoon Lee

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

Objective: The aim of this study was to develop a predictive model of objective oropharyngeal obstructive sleep apnea (OSA) surgery outcomes including success rate and apnea-hypopnea index (AHI) reduction ratio in adult OSA patients. Study design: Retrospective outcome research. Methods: All subjects with OSA who underwent oropharyngeal and/or nasal surgery and were followed for at least 3 months were enrolled in this study. Demographic, anatomical [tonsil size (TS) and palate-tongue position (PTP) grade (Gr)], and polysomnographic parameters were analyzed. The AHI reduction ratio (%) was defined as [(postoperative AHI—preoperative AHI) x 100 / postoperative AHI], and surgical success was defined as a ≥ 50% reduction in preoperative AHI with a postoperative AHI < 20. Results: A total of 156 consecutive OSAS adult patients (mean age ± SD = 38.9 ± 9.6, M / F = 149 / 7) were included in this study. The best predictive equation by Forward Selection likelihood ratio (LR) logistic regression analysis was: ln (P_x / 1 - P_x ) = 1:518 - 0:039 x Age + 1:392 x TSGr - 0.803 x PTPGr The best predictive equation according to stepwise multiple linear regression analysis was: AHIreductionratio = -39.464 + (32.752 x TSGr) + (2.623 x AHI) - (2.542 x Arousalindex) +[1.245 x MinimumSaO₂(%)] - [0.599 x Snoring(%)] (TS/PTP Gr = 1 if TS/PTP Gr 3 or 4, TS/PTP Gr = 0 if TS/PTP Gr 1 or 2) Conclusion: The predictive models for oropharyngeal surgery described in this study may be useful for planning surgical treatments and improving objective outcomes in adult OSA patients.

Original language	English
Article number	e0185201
Journal	PloS one
Volume	12
Issue number	9
DOIs	https://doi.org/10.1371/journal.pone.0185201
Publication status	Published - 2017 Sept
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2017 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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title = "Predictive models of objective oropharyngeal OSA surgery outcomes: Success rate and AHI reduction ratio",

abstract = "Objective: The aim of this study was to develop a predictive model of objective oropharyngeal obstructive sleep apnea (OSA) surgery outcomes including success rate and apnea-hypopnea index (AHI) reduction ratio in adult OSA patients. Study design: Retrospective outcome research. Methods: All subjects with OSA who underwent oropharyngeal and/or nasal surgery and were followed for at least 3 months were enrolled in this study. Demographic, anatomical [tonsil size (TS) and palate-tongue position (PTP) grade (Gr)], and polysomnographic parameters were analyzed. The AHI reduction ratio (%) was defined as [(postoperative AHI—preoperative AHI) x 100 / postoperative AHI], and surgical success was defined as a ≥ 50% reduction in preoperative AHI with a postoperative AHI < 20. Results: A total of 156 consecutive OSAS adult patients (mean age ± SD = 38.9 ± 9.6, M / F = 149 / 7) were included in this study. The best predictive equation by Forward Selection likelihood ratio (LR) logistic regression analysis was: ln (Px / 1 - Px ) = 1:518 - 0:039 x Age + 1:392 x TSGr - 0.803 x PTPGr The best predictive equation according to stepwise multiple linear regression analysis was: AHIreductionratio = -39.464 + (32.752 x TSGr) + (2.623 x AHI) - (2.542 x Arousalindex) +[1.245 x MinimumSaO2(%)] - [0.599 x Snoring(%)] (TS/PTP Gr = 1 if TS/PTP Gr 3 or 4, TS/PTP Gr = 0 if TS/PTP Gr 1 or 2) Conclusion: The predictive models for oropharyngeal surgery described in this study may be useful for planning surgical treatments and improving objective outcomes in adult OSA patients.",

author = "Choi, {Ji Ho} and Lee, {Jae Yong} and Jaehyung Cha and Kangwoo Kim and Hong, {Seung No} and Lee, {Seung Hoon}",

note = "Publisher Copyright: {\textcopyright} 2017 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.",

year = "2017",

month = sep,

doi = "10.1371/journal.pone.0185201",

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AU - Choi, Ji Ho

AU - Lee, Jae Yong

AU - Cha, Jaehyung

AU - Kim, Kangwoo

AU - Hong, Seung No

AU - Lee, Seung Hoon

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PY - 2017/9

Y1 - 2017/9

N2 - Objective: The aim of this study was to develop a predictive model of objective oropharyngeal obstructive sleep apnea (OSA) surgery outcomes including success rate and apnea-hypopnea index (AHI) reduction ratio in adult OSA patients. Study design: Retrospective outcome research. Methods: All subjects with OSA who underwent oropharyngeal and/or nasal surgery and were followed for at least 3 months were enrolled in this study. Demographic, anatomical [tonsil size (TS) and palate-tongue position (PTP) grade (Gr)], and polysomnographic parameters were analyzed. The AHI reduction ratio (%) was defined as [(postoperative AHI—preoperative AHI) x 100 / postoperative AHI], and surgical success was defined as a ≥ 50% reduction in preoperative AHI with a postoperative AHI < 20. Results: A total of 156 consecutive OSAS adult patients (mean age ± SD = 38.9 ± 9.6, M / F = 149 / 7) were included in this study. The best predictive equation by Forward Selection likelihood ratio (LR) logistic regression analysis was: ln (Px / 1 - Px ) = 1:518 - 0:039 x Age + 1:392 x TSGr - 0.803 x PTPGr The best predictive equation according to stepwise multiple linear regression analysis was: AHIreductionratio = -39.464 + (32.752 x TSGr) + (2.623 x AHI) - (2.542 x Arousalindex) +[1.245 x MinimumSaO2(%)] - [0.599 x Snoring(%)] (TS/PTP Gr = 1 if TS/PTP Gr 3 or 4, TS/PTP Gr = 0 if TS/PTP Gr 1 or 2) Conclusion: The predictive models for oropharyngeal surgery described in this study may be useful for planning surgical treatments and improving objective outcomes in adult OSA patients.

AB - Objective: The aim of this study was to develop a predictive model of objective oropharyngeal obstructive sleep apnea (OSA) surgery outcomes including success rate and apnea-hypopnea index (AHI) reduction ratio in adult OSA patients. Study design: Retrospective outcome research. Methods: All subjects with OSA who underwent oropharyngeal and/or nasal surgery and were followed for at least 3 months were enrolled in this study. Demographic, anatomical [tonsil size (TS) and palate-tongue position (PTP) grade (Gr)], and polysomnographic parameters were analyzed. The AHI reduction ratio (%) was defined as [(postoperative AHI—preoperative AHI) x 100 / postoperative AHI], and surgical success was defined as a ≥ 50% reduction in preoperative AHI with a postoperative AHI < 20. Results: A total of 156 consecutive OSAS adult patients (mean age ± SD = 38.9 ± 9.6, M / F = 149 / 7) were included in this study. The best predictive equation by Forward Selection likelihood ratio (LR) logistic regression analysis was: ln (Px / 1 - Px ) = 1:518 - 0:039 x Age + 1:392 x TSGr - 0.803 x PTPGr The best predictive equation according to stepwise multiple linear regression analysis was: AHIreductionratio = -39.464 + (32.752 x TSGr) + (2.623 x AHI) - (2.542 x Arousalindex) +[1.245 x MinimumSaO2(%)] - [0.599 x Snoring(%)] (TS/PTP Gr = 1 if TS/PTP Gr 3 or 4, TS/PTP Gr = 0 if TS/PTP Gr 1 or 2) Conclusion: The predictive models for oropharyngeal surgery described in this study may be useful for planning surgical treatments and improving objective outcomes in adult OSA patients.

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DO - 10.1371/journal.pone.0185201

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Predictive models of objective oropharyngeal OSA surgery outcomes: Success rate and AHI reduction ratio

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