Preliminary results of a prototype C-shaped PET designed for an in-beam PET system

Hyun Il Kim; Yong Hyun Chung; Kisung Lee; Kyeong Min Kim; Yongkwon Kim; Jinhun Joung

doi:10.1016/j.nima.2016.03.021

Preliminary results of a prototype C-shaped PET designed for an in-beam PET system

Hyun Il Kim, Yong Hyun Chung, Kisung Lee, Kyeong Min Kim, Yongkwon Kim, Jinhun Joung

School of Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Positron emission tomography (PET) can be utilized in particle beam therapy to verify the dose distribution of the target volume as well as the accuracy of the treatment. We present an in-beam PET scanner that can be integrated into a particle beam therapy system. The proposed PET scanner consisted of 14 detector modules arranged in a C-shape to avoid blockage of the particle beam line by the detector modules. Each detector module was composed of a 9×9 array of 4.0 mm×4.0 mm×20.0 mm LYSO crystals optically coupled to four 29-mm-diameter PMTs using the photomultiplier-quadrant-sharing (PQS) technique. In this study, a Geant4 Application for Tomographic Emission (GATE) simulation study was conducted to design a C-shaped PET scanner and then experimental evaluation of the proposed design was performed. The spatial resolution and sensitivity were measured according to NEMA NU2-2007 standards and were 6.1 mm and 5.61 cps/kBq, respectively, which is in good agreement with our simulation, with an error rate of 12.0%. Taken together, our results demonstrate the feasibility of the proposed C-shaped in-beam PET system, which we expect will be useful for measuring dose distribution in particle therapy.

Original language	English
Pages (from-to)	57-62
Number of pages	6
Journal	Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume	822
DOIs	https://doi.org/10.1016/j.nima.2016.03.021
Publication status	Published - 2016 Jun 21

Bibliographical note

Funding Information:
This research was supported by the Korea Institute of Radiological & Medical Sciences funded by the Ministry of Science, ICT & Future Planning (No. 1711021927) .

Publisher Copyright:
© 2016 Elsevier B.V. All rights reserved.

Keywords

C-shaped scanner
Monte Carlo simulation
NEMA standard
Particle therapy
Positron emission tomography

ASJC Scopus subject areas

Nuclear and High Energy Physics
Instrumentation

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10.1016/j.nima.2016.03.021

Cite this

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title = "Preliminary results of a prototype C-shaped PET designed for an in-beam PET system",

abstract = "Positron emission tomography (PET) can be utilized in particle beam therapy to verify the dose distribution of the target volume as well as the accuracy of the treatment. We present an in-beam PET scanner that can be integrated into a particle beam therapy system. The proposed PET scanner consisted of 14 detector modules arranged in a C-shape to avoid blockage of the particle beam line by the detector modules. Each detector module was composed of a 9×9 array of 4.0 mm×4.0 mm×20.0 mm LYSO crystals optically coupled to four 29-mm-diameter PMTs using the photomultiplier-quadrant-sharing (PQS) technique. In this study, a Geant4 Application for Tomographic Emission (GATE) simulation study was conducted to design a C-shaped PET scanner and then experimental evaluation of the proposed design was performed. The spatial resolution and sensitivity were measured according to NEMA NU2-2007 standards and were 6.1 mm and 5.61 cps/kBq, respectively, which is in good agreement with our simulation, with an error rate of 12.0%. Taken together, our results demonstrate the feasibility of the proposed C-shaped in-beam PET system, which we expect will be useful for measuring dose distribution in particle therapy.",

keywords = "C-shaped scanner, Monte Carlo simulation, NEMA standard, Particle therapy, Positron emission tomography",

author = "Kim, {Hyun Il} and Chung, {Yong Hyun} and Kisung Lee and Kim, {Kyeong Min} and Yongkwon Kim and Jinhun Joung",

note = "Funding Information: This research was supported by the Korea Institute of Radiological & Medical Sciences funded by the Ministry of Science, ICT & Future Planning (No. 1711021927) . Publisher Copyright: {\textcopyright} 2016 Elsevier B.V. All rights reserved.",

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doi = "10.1016/j.nima.2016.03.021",

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AU - Kim, Kyeong Min

AU - Kim, Yongkwon

AU - Joung, Jinhun

N1 - Funding Information: This research was supported by the Korea Institute of Radiological & Medical Sciences funded by the Ministry of Science, ICT & Future Planning (No. 1711021927) . Publisher Copyright: © 2016 Elsevier B.V. All rights reserved.

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N2 - Positron emission tomography (PET) can be utilized in particle beam therapy to verify the dose distribution of the target volume as well as the accuracy of the treatment. We present an in-beam PET scanner that can be integrated into a particle beam therapy system. The proposed PET scanner consisted of 14 detector modules arranged in a C-shape to avoid blockage of the particle beam line by the detector modules. Each detector module was composed of a 9×9 array of 4.0 mm×4.0 mm×20.0 mm LYSO crystals optically coupled to four 29-mm-diameter PMTs using the photomultiplier-quadrant-sharing (PQS) technique. In this study, a Geant4 Application for Tomographic Emission (GATE) simulation study was conducted to design a C-shaped PET scanner and then experimental evaluation of the proposed design was performed. The spatial resolution and sensitivity were measured according to NEMA NU2-2007 standards and were 6.1 mm and 5.61 cps/kBq, respectively, which is in good agreement with our simulation, with an error rate of 12.0%. Taken together, our results demonstrate the feasibility of the proposed C-shaped in-beam PET system, which we expect will be useful for measuring dose distribution in particle therapy.

AB - Positron emission tomography (PET) can be utilized in particle beam therapy to verify the dose distribution of the target volume as well as the accuracy of the treatment. We present an in-beam PET scanner that can be integrated into a particle beam therapy system. The proposed PET scanner consisted of 14 detector modules arranged in a C-shape to avoid blockage of the particle beam line by the detector modules. Each detector module was composed of a 9×9 array of 4.0 mm×4.0 mm×20.0 mm LYSO crystals optically coupled to four 29-mm-diameter PMTs using the photomultiplier-quadrant-sharing (PQS) technique. In this study, a Geant4 Application for Tomographic Emission (GATE) simulation study was conducted to design a C-shaped PET scanner and then experimental evaluation of the proposed design was performed. The spatial resolution and sensitivity were measured according to NEMA NU2-2007 standards and were 6.1 mm and 5.61 cps/kBq, respectively, which is in good agreement with our simulation, with an error rate of 12.0%. Taken together, our results demonstrate the feasibility of the proposed C-shaped in-beam PET system, which we expect will be useful for measuring dose distribution in particle therapy.

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ER -

Preliminary results of a prototype C-shaped PET designed for an in-beam PET system

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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