Abstract
Biodegradable hydrogels based on synthetic PHEA and IPN type composite hydrogel with chitosan, a natural carbohydrate polymer, were prepared by crosslinking using glutaraldehyde in aqueous mixture. Relatively strong hydrogels were formed in a shaped mold. Preparation of crosslinked gels and their swelling behavior depending on the composition, medium, and pH of solution are investigated. The porous morphology of scaffolds, obtained by freeze-drying method, was observed by scanning electron microscopy. Also preliminary results/on hydrolytic degradation and cytotoxicity test of the hydrogel are included.
Original language | English |
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Pages (from-to) | 943-948 |
Number of pages | 6 |
Journal | Polymer Journal |
Volume | 36 |
Issue number | 12 |
DOIs | |
Publication status | Published - 2004 |
Externally published | Yes |
Bibliographical note
Funding Information:Acknowledgment. This work was supported by the Korea Research Foundation Grant (KRF-2004-005-D00070).
Keywords
- Biodegradation
- Chitosan
- Hydrogel
- Polyhydroxyethyl aspartamide
- Scaffold
- Swelling Behavior
- pH-Sensitive
ASJC Scopus subject areas
- Polymers and Plastics
- Materials Chemistry