Biodegradable hydrogels based on synthetic PHEA and IPN type composite hydrogel with chitosan, a natural carbohydrate polymer, were prepared by crosslinking using glutaraldehyde in aqueous mixture. Relatively strong hydrogels were formed in a shaped mold. Preparation of crosslinked gels and their swelling behavior depending on the composition, medium, and pH of solution are investigated. The porous morphology of scaffolds, obtained by freeze-drying method, was observed by scanning electron microscopy. Also preliminary results/on hydrolytic degradation and cytotoxicity test of the hydrogel are included.
Bibliographical noteFunding Information:
Acknowledgment. This work was supported by the Korea Research Foundation Grant (KRF-2004-005-D00070).
- Polyhydroxyethyl aspartamide
- Swelling Behavior
ASJC Scopus subject areas
- Polymers and Plastics
- Materials Chemistry