Primary large cell neuroendocrine carcinoma of the breast: Radiologic and pathologic findings

Jin Woo Kim, Ok Hee Woo, Kyu Ran Cho, Bo Kyung Seo, Hwan Seok Yong, Aeree Kim, Eun Young Kang

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Some breast neoplasms are classified as primary neuroendocrine carcinomas because they are positive for neuroendocrine markers. Although neuroendocrine carcinomas can originate from various organs of the body, primary neuroendocrine carcinomas of the breast are extremely rare. The diagnosis of primary neuroendocrine carcinoma of the breast can only be made if nonmammary sites are confidently excluded or if an in situ component can be found. Here we report a primary large-cell neuroendocrine carcinoma (LCNL) involving the left breast. Breast ultrasonography revealed a lobulated, heterogeneous, low-echoic mass in the left breast, and the lesion ap-peared as a well-defined, highly-enhancing mass on a chest computed tomography scan. Ultrasound-guided core needle biopsy was performed on the mass, and primary LCNC was confirmed by histopathologic examination.

Original languageEnglish
Pages (from-to)1118-1120
Number of pages3
JournalJournal of Korean medical science
Issue number6
Publication statusPublished - 2008 Dec


  • Breast
  • Large cell neuroendocrine carcinoma
  • Tomography
  • Ultrasonography
  • X-Ray computed

ASJC Scopus subject areas

  • General Medicine


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