Primary large cell neuroendocrine carcinoma of the breast: Radiologic and pathologic findings

Jin Woo Kim, Ok Hee Woo, Kyu Ran Cho, Bo Kyung Seo, Hwan Seok Yong, Aeree Kim, Eun Young Kang

    Research output: Contribution to journalArticlepeer-review

    20 Citations (Scopus)

    Abstract

    Some breast neoplasms are classified as primary neuroendocrine carcinomas because they are positive for neuroendocrine markers. Although neuroendocrine carcinomas can originate from various organs of the body, primary neuroendocrine carcinomas of the breast are extremely rare. The diagnosis of primary neuroendocrine carcinoma of the breast can only be made if nonmammary sites are confidently excluded or if an in situ component can be found. Here we report a primary large-cell neuroendocrine carcinoma (LCNL) involving the left breast. Breast ultrasonography revealed a lobulated, heterogeneous, low-echoic mass in the left breast, and the lesion ap-peared as a well-defined, highly-enhancing mass on a chest computed tomography scan. Ultrasound-guided core needle biopsy was performed on the mass, and primary LCNC was confirmed by histopathologic examination.

    Original languageEnglish
    Pages (from-to)1118-1120
    Number of pages3
    JournalJournal of Korean medical science
    Volume23
    Issue number6
    DOIs
    Publication statusPublished - 2008 Dec

    Keywords

    • Breast
    • Large cell neuroendocrine carcinoma
    • Tomography
    • Ultrasonography
    • X-Ray computed

    ASJC Scopus subject areas

    • General Medicine

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