Primary pulmonary Ewing's sarcoma/primitive neuroectodermal tumor in a 67-year-old man

Young Lee Yoon, Hoon Kim Do, Hye Lee Ji, Sang Choi Jong, Ho In Kwang, Whan Oh Yu, Hwan Cho Kyung, Kyun Roh Yong

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32 Citations (Scopus)

Abstract

Extraskeletal Ewing's sarcoma (EES) is a branch of neuroectodermal tumor (PNET), which is very rare soft tissue sarcoma. We report a case of EES/PNET arising is the lung of a 67-yr-old man. Computed tomography, bone scintigraphy, and positron emission tomography confirmed the mass to have a primary pulmonary origin. The mass showed positive reactivity in the Periodic Acid Schiff (PAS) stain and MIC-2 immunoreactivity in immunohistochemical stain. Fluorescence in situ hybridization (FISH) was performed, which revealed an EWSR1 (Ewing sarcoma breakpoint region 1) 22q12 rearrangement. The diagnosis was confirmed both pathologically and genetically. The mass lesion was resected, and the patient is currently undergoing chemotherapy.

Original languageEnglish
Pages (from-to)S159-S163
JournalJournal of Korean medical science
Volume22
Issue numberSUPPL.
DOIs
Publication statusPublished - 2007 Sept
Externally publishedYes

Keywords

  • Ewing's
  • Lung
  • Neuroectodermal tumors
  • Peripheral
  • Primitive
  • Sarcoma

ASJC Scopus subject areas

  • General Medicine

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