Probing 3-hydroxyflavone for In vitro glycorandomization of flavonols by YjiC

Ramesh Prasad Pandey; Prakash Parajuli; Niranjan Koirala; Je Won Park; Jae Kyung Sohng

doi:10.1128/AEM.02057-13

Probing 3-hydroxyflavone for In vitro glycorandomization of flavonols by YjiC

Ramesh Prasad Pandey
, Prakash Parajuli
, Niranjan Koirala
, Je Won Park
, Jae Kyung Sohng^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

51 Citations (Scopus)

Abstract

The glycosylation of five different flavonols, fisetin, quercetin, myricetin, kaempferol, and 3-hydroxyflavone, was achieved by applying YjiC. 3-Hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-D/L-sugars. This study unlocked the possibilities of the glycodiversification of flavonols and the generation of novel compounds as future therapeutics.

Original language	English
Pages (from-to)	6833-6838
Number of pages	6
Journal	Applied and environmental microbiology
Volume	79
Issue number	21
DOIs	https://doi.org/10.1128/AEM.02057-13
Publication status	Published - 2013
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Food Science
Applied Microbiology and Biotechnology
Ecology

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title = "Probing 3-hydroxyflavone for In vitro glycorandomization of flavonols by YjiC",

abstract = "The glycosylation of five different flavonols, fisetin, quercetin, myricetin, kaempferol, and 3-hydroxyflavone, was achieved by applying YjiC. 3-Hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-D/L-sugars. This study unlocked the possibilities of the glycodiversification of flavonols and the generation of novel compounds as future therapeutics.",

author = "Pandey, \{Ramesh Prasad\} and Prakash Parajuli and Niranjan Koirala and Park, \{Je Won\} and Sohng, \{Jae Kyung\}",

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AU - Pandey, Ramesh Prasad

AU - Parajuli, Prakash

AU - Koirala, Niranjan

AU - Park, Je Won

AU - Sohng, Jae Kyung

PY - 2013

Y1 - 2013

N2 - The glycosylation of five different flavonols, fisetin, quercetin, myricetin, kaempferol, and 3-hydroxyflavone, was achieved by applying YjiC. 3-Hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-D/L-sugars. This study unlocked the possibilities of the glycodiversification of flavonols and the generation of novel compounds as future therapeutics.

AB - The glycosylation of five different flavonols, fisetin, quercetin, myricetin, kaempferol, and 3-hydroxyflavone, was achieved by applying YjiC. 3-Hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-D/L-sugars. This study unlocked the possibilities of the glycodiversification of flavonols and the generation of novel compounds as future therapeutics.

UR - https://www.scopus.com/pages/publications/84886925183

U2 - 10.1128/AEM.02057-13

DO - 10.1128/AEM.02057-13

M3 - Article

C2 - 23974133

AN - SCOPUS:84886925183

SN - 0099-2240

VL - 79

SP - 6833

EP - 6838

JO - Applied and environmental microbiology

JF - Applied and environmental microbiology

IS - 21

ER -

Probing 3-hydroxyflavone for In vitro glycorandomization of flavonols by YjiC

Abstract

ASJC Scopus subject areas

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