Production of mycelia and exo-biopolymer from molasses by Cordyceps sinensis 16 in submerged culture

  • S. H. Cha
  • , J. S. Lim
  • , C. S. Yoon
  • , J. H. Koh
  • , H. I. Chang
  • , S. W. Kim*
  • *Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    37 Citations (Scopus)

    Abstract

    The molecular weight of exo-biopolymer obtained from a submerged culture of Cordyceps sinensis 16 consisted of a main unit and a subunit of 126 and 68 kDa, respectively. The optimal medium for the production of mycelia and exo-biopolymer was determined to be molasses containing 2% sucrose, 0.9% yeast extract, 0.3% K2HPO4, and 0.4% CaCl2. Using optimized medium, maximum productions of mycelia and exo-biopolymer in shake-flask culture were 54.0 g/L and 28.4 g/L, respectively. This study suggests that large-scale production of mycelia and exo-biopolymer by C. sinensis 16 is possible in submerged culture.

    Original languageEnglish
    Pages (from-to)165-168
    Number of pages4
    JournalBioresource technology
    Volume98
    Issue number1
    DOIs
    Publication statusPublished - 2007 Jan

    Bibliographical note

    Funding Information:
    This study was partly supported by research grants from Nel Biotech Co., Ltd. and partly the Korea Science and Engineering Foundation (KOSEF) through the Applied Rheology Center (ARC), an official KOSEF-created Engineering Research Center (ERC) at Korea University, Seoul, Korea.

    Copyright:
    Copyright 2011 Elsevier B.V., All rights reserved.

    Keywords

    • Cordyceps sinensis
    • Exo-biopolymer
    • Molasses
    • Optimization

    ASJC Scopus subject areas

    • Bioengineering
    • Environmental Engineering
    • Renewable Energy, Sustainability and the Environment
    • Waste Management and Disposal

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