(Figure Presented) Take your PIC: Cell-permeable and biocompatible polyion-induced complex (PIC) nanoparticles were developed consisting of a negatively charged polymer along with a positively charged polymer conjugated to a near-infrared fluorophore and a protein-kinase-specific peptide. Owing to profound changes in fluorescence, the PIC nanoparticle is an attractive probe for protein kinase A (PKA) in single living cells. ATP = adenosine triphosphate, ADP = adenosine diphosphate.
|Number of pages||4|
|Journal||Angewandte Chemie - International Edition|
|Publication status||Published - 2007|
- Cell imaging
- Fluorescent probes
- Protein kinases
ASJC Scopus subject areas