Proteome reactivity profiling for the discrimination of pathogenic bacteria

Jun Seok Lee; Young Hwa Yoo; Won Seok Han; Jin Kak Lee; Chang No Yoon

doi:10.1039/c4cc00320a

Proteome reactivity profiling for the discrimination of pathogenic bacteria

Jun Seok Lee, Young Hwa Yoo, Won Seok Han, Jin Kak Lee, Chang No Yoon

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Diverse proteome reactivity profiles were obtained using small-molecule electrophiles. Based on the cross-reactivity profile, each protein generated a unique reactivity fingerprint. Here, we report the first proteome reactivity signature-based discrimination of 11 bacteria. Perfect differentiation of 11 bacteria can be achieved using 2 benzyl-halide probes.

Original language	English
Pages (from-to)	4347-4350
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	33
DOIs	https://doi.org/10.1039/c4cc00320a
Publication status	Published - 2014 Mar 27
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c4cc00320a

Cite this

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title = "Proteome reactivity profiling for the discrimination of pathogenic bacteria",

abstract = "Diverse proteome reactivity profiles were obtained using small-molecule electrophiles. Based on the cross-reactivity profile, each protein generated a unique reactivity fingerprint. Here, we report the first proteome reactivity signature-based discrimination of 11 bacteria. Perfect differentiation of 11 bacteria can be achieved using 2 benzyl-halide probes.",

author = "Lee, {Jun Seok} and Yoo, {Young Hwa} and Han, {Won Seok} and Lee, {Jin Kak} and Yoon, {Chang No}",

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AU - Lee, Jun Seok

AU - Yoo, Young Hwa

AU - Han, Won Seok

AU - Lee, Jin Kak

AU - Yoon, Chang No

PY - 2014/3/27

Y1 - 2014/3/27

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AB - Diverse proteome reactivity profiles were obtained using small-molecule electrophiles. Based on the cross-reactivity profile, each protein generated a unique reactivity fingerprint. Here, we report the first proteome reactivity signature-based discrimination of 11 bacteria. Perfect differentiation of 11 bacteria can be achieved using 2 benzyl-halide probes.

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DO - 10.1039/c4cc00320a

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JO - Chemical Communications

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Proteome reactivity profiling for the discrimination of pathogenic bacteria

Abstract

ASJC Scopus subject areas

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