Abstract This study proposes to determine the correlation between the Volume Pulse Height (VPH) measured by nuclear emulsion and Linear Energy Transfer (LET) calculated by Monte Carlo simulation based on Geant4. The nuclear emulsion was irradiated at the National Cancer Center (NCC) with a therapeutic proton beam and was installed at 5.2 m distance from the beam nozzle structure with various thicknesses of water-equivalent material (PMMA) blocks to position with specific positions along the Bragg curve. After the beam exposure and development of the emulsion films, the films were scanned by S-UTS developed in Nagoya University. The proton tracks in the scanned films were reconstructed using the 'NETSCAN' method. Through this procedure, the VPH can be derived from each reconstructed proton track at each position along the Bragg curve. The VPH value indicates the magnitude of energy loss in proton track. By comparison with the simulation results obtained using Geant4, we found the correlation between the LET calculated by Monte Carlo simulation and the VPH measured by the nuclear emulsion.
|Number of pages||8|
|Journal||Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms|
|Publication status||Published - 2015 Apr 15|
Bibliographical noteFunding Information:
This work was partly supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (National Research Foundation of Korea – 2012 – K1A3A1A21 – 2010-0026071). This study was partly supported also by funds from a research project of the National Cancer Center of Korea (Nos. NCC-1210210 ). This work was partly supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government ( MEST ) (Nuclear Energy Research Infrastructure Program, 2011-0019054). Also we thank the International Associated Laboratory “France-Korea Particle Physics and e-science Laboratory” (FKPPL) for its regular support.
© 2015 Elsevier B.V. All rights reserved.
- Bragg curve
- Linear Energy Transfer (LET)
- Nuclear emulsion
- Proton therapy
- Volume Pulse Height (VPH)
ASJC Scopus subject areas
- Nuclear and High Energy Physics