Protuboxepins A and B and protubonines A and B from the marine-derived fungus Aspergillus sp. SF-5044

Sang Un Lee, Yukihiro Asami, Dongho Lee, Jae Hyuk Jang, Jong Seog Ahn, Hyuncheol Oh

    Research output: Contribution to journalArticlepeer-review

    78 Citations (Scopus)

    Abstract

    Two new oxepin-containing (1 and 2) and two diketopiperazine-type alkaloids (3 and 4) have been isolated from an EtOAc extract of the marine-derived fungus Aspergillus sp. SF-5044. The structures of these metabolites were determined through analysis of NMR and MS data, along with Marfey's method. Compound 1 showed weak growth inhibitory activity against a small panel of cell lines. (Chemical Equation Presented).

    Original languageEnglish
    Pages (from-to)1284-1287
    Number of pages4
    JournalJournal of Natural Products
    Volume74
    Issue number5
    DOIs
    Publication statusPublished - 2011 May 27

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Molecular Medicine
    • Pharmacology
    • Pharmaceutical Science
    • Drug Discovery
    • Complementary and alternative medicine
    • Organic Chemistry

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