Protuboxepins A and B and protubonines A and B from the marine-derived fungus Aspergillus sp. SF-5044

Sang Un Lee; Yukihiro Asami; Dongho Lee; Jae Hyuk Jang; Jong Seog Ahn; Hyuncheol Oh

doi:10.1021/np100880b

Protuboxepins A and B and protubonines A and B from the marine-derived fungus Aspergillus sp. SF-5044

Sang Un Lee, Yukihiro Asami, Dongho Lee, Jae Hyuk Jang, Jong Seog Ahn, Hyuncheol Oh

Research output: Contribution to journal › Article › peer-review

79 Citations (Scopus)

Abstract

Two new oxepin-containing (1 and 2) and two diketopiperazine-type alkaloids (3 and 4) have been isolated from an EtOAc extract of the marine-derived fungus Aspergillus sp. SF-5044. The structures of these metabolites were determined through analysis of NMR and MS data, along with Marfey's method. Compound 1 showed weak growth inhibitory activity against a small panel of cell lines. (Chemical Equation Presented).

Original language	English
Pages (from-to)	1284-1287
Number of pages	4
Journal	Journal of Natural Products
Volume	74
Issue number	5
DOIs	https://doi.org/10.1021/np100880b
Publication status	Published - 2011 May 27

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/np100880b

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abstract = "Two new oxepin-containing (1 and 2) and two diketopiperazine-type alkaloids (3 and 4) have been isolated from an EtOAc extract of the marine-derived fungus Aspergillus sp. SF-5044. The structures of these metabolites were determined through analysis of NMR and MS data, along with Marfey's method. Compound 1 showed weak growth inhibitory activity against a small panel of cell lines. (Chemical Equation Presented).",

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AU - Lee, Sang Un

AU - Asami, Yukihiro

AU - Lee, Dongho

AU - Jang, Jae Hyuk

AU - Ahn, Jong Seog

AU - Oh, Hyuncheol

PY - 2011/5/27

Y1 - 2011/5/27

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AB - Two new oxepin-containing (1 and 2) and two diketopiperazine-type alkaloids (3 and 4) have been isolated from an EtOAc extract of the marine-derived fungus Aspergillus sp. SF-5044. The structures of these metabolites were determined through analysis of NMR and MS data, along with Marfey's method. Compound 1 showed weak growth inhibitory activity against a small panel of cell lines. (Chemical Equation Presented).

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Protuboxepins A and B and protubonines A and B from the marine-derived fungus Aspergillus sp. SF-5044

Abstract

ASJC Scopus subject areas

UN SDGs

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