Pt-catalyzed hydrative cyclization of 2-enynylbenzaldehydes and its application to faveline synthesis

Chang Ho Oh; Sung Min Lee; Chang Seop Hong

doi:10.1021/01100255z

Pt-catalyzed hydrative cyclization of 2-enynylbenzaldehydes and its application to faveline synthesis

Chang Ho Oh, Sung Min Lee, Chang Seop Hong

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

"Chemical Equation Presented" Various 2-[6-en-1-ynyl] benzaldehydes and their analogues were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic platinum-carbene complex, which would subsequently undergo hydration to afford the tricyclic products in good yields with excellent stereoselectivities. This hydrative cyclization was also applied to the faveline synthesis.

Original language	English
Pages (from-to)	1308-1311
Number of pages	4
Journal	Organic Letters
Volume	12
Issue number	6
DOIs	https://doi.org/10.1021/01100255z
Publication status	Published - 2010 Mar 19
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/01100255z

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title = "Pt-catalyzed hydrative cyclization of 2-enynylbenzaldehydes and its application to faveline synthesis",

abstract = "{"}Chemical Equation Presented{"} Various 2-[6-en-1-ynyl] benzaldehydes and their analogues were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic platinum-carbene complex, which would subsequently undergo hydration to afford the tricyclic products in good yields with excellent stereoselectivities. This hydrative cyclization was also applied to the faveline synthesis.",

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AU - Oh, Chang Ho

AU - Lee, Sung Min

AU - Hong, Chang Seop

PY - 2010/3/19

Y1 - 2010/3/19

N2 - "Chemical Equation Presented" Various 2-[6-en-1-ynyl] benzaldehydes and their analogues were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic platinum-carbene complex, which would subsequently undergo hydration to afford the tricyclic products in good yields with excellent stereoselectivities. This hydrative cyclization was also applied to the faveline synthesis.

AB - "Chemical Equation Presented" Various 2-[6-en-1-ynyl] benzaldehydes and their analogues were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic platinum-carbene complex, which would subsequently undergo hydration to afford the tricyclic products in good yields with excellent stereoselectivities. This hydrative cyclization was also applied to the faveline synthesis.

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U2 - 10.1021/01100255z

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JO - Organic Letters

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Pt-catalyzed hydrative cyclization of 2-enynylbenzaldehydes and its application to faveline synthesis

Abstract

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