Pt-catalyzed hydrative cyclization of 2-enynylbenzaldehydes and its application to faveline synthesis

Chang Ho Oh; Sung Min Lee; Chang Seop Hong

doi:10.1021/01100255z

Pt-catalyzed hydrative cyclization of 2-enynylbenzaldehydes and its application to faveline synthesis

Chang Ho Oh
, Sung Min Lee
, Chang Seop Hong

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

"Chemical Equation Presented" Various 2-[6-en-1-ynyl] benzaldehydes and their analogues were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic platinum-carbene complex, which would subsequently undergo hydration to afford the tricyclic products in good yields with excellent stereoselectivities. This hydrative cyclization was also applied to the faveline synthesis.

Original language	English
Pages (from-to)	1308-1311
Number of pages	4
Journal	Organic Letters
Volume	12
Issue number	6
DOIs	https://doi.org/10.1021/01100255z
Publication status	Published - 2010 Mar 19
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Access to Document

10.1021/01100255z

Cite this

@article{e5f516b59b4c4e72b29346d88e04c527,

title = "Pt-catalyzed hydrative cyclization of 2-enynylbenzaldehydes and its application to faveline synthesis",

abstract = "{"}Chemical Equation Presented{"} Various 2-[6-en-1-ynyl] benzaldehydes and their analogues were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic platinum-carbene complex, which would subsequently undergo hydration to afford the tricyclic products in good yields with excellent stereoselectivities. This hydrative cyclization was also applied to the faveline synthesis.",

author = "Oh, \{Chang Ho\} and Lee, \{Sung Min\} and Hong, \{Chang Seop\}",

year = "2010",

month = mar,

day = "19",

doi = "10.1021/01100255z",

language = "English",

volume = "12",

pages = "1308--1311",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "6",

}

TY - JOUR

T1 - Pt-catalyzed hydrative cyclization of 2-enynylbenzaldehydes and its application to faveline synthesis

AU - Oh, Chang Ho

AU - Lee, Sung Min

AU - Hong, Chang Seop

PY - 2010/3/19

Y1 - 2010/3/19

N2 - "Chemical Equation Presented" Various 2-[6-en-1-ynyl] benzaldehydes and their analogues were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic platinum-carbene complex, which would subsequently undergo hydration to afford the tricyclic products in good yields with excellent stereoselectivities. This hydrative cyclization was also applied to the faveline synthesis.

AB - "Chemical Equation Presented" Various 2-[6-en-1-ynyl] benzaldehydes and their analogues were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic platinum-carbene complex, which would subsequently undergo hydration to afford the tricyclic products in good yields with excellent stereoselectivities. This hydrative cyclization was also applied to the faveline synthesis.

UR - https://www.scopus.com/pages/publications/77949862535

U2 - 10.1021/01100255z

DO - 10.1021/01100255z

M3 - Article

C2 - 20184345

AN - SCOPUS:77949862535

SN - 1523-7060

VL - 12

SP - 1308

EP - 1311

JO - Organic Letters

JF - Organic Letters

IS - 6

ER -

Pt-catalyzed hydrative cyclization of 2-enynylbenzaldehydes and its application to faveline synthesis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this