Pulmonary Toxicity and Proteomic Analysis in Bronchoalveolar Lavage Fluids and Lungs of Rats Exposed to Copper Oxide Nanoparticles

Pharmacology, Toxicology and Pharmaceutical Science

• Copper Oxide Nanoparticle 100%
• Immunotoxicity 100%
• Lung Toxicity 100%
• Cytotoxicity 100%
• Western Blot 50%
• Tumor Necrosis Factor 50%
• Cytokine 50%
• Synthetase 50%
• Catalase 50%
• Biological Marker 50%
• Proteasome 50%
• Protein 50%
• Lactic Acid 50%
• Manganese Superoxide Dismutase 50%
• Peroxiredoxin 2 50%
• Glutathione Peroxidase 1 50%
• Heat Shock Protein 50%
• Lipocortin 2 50%
• Macrophage Inflammatory Protein 2 50%

Keyphrases

• Proteomic Analysis 100%
• Lung 100%
• Bronchoalveolar Lavage Fluid 100%
• Toxicity Analysis 100%
• Copper Oxide Nanoparticles (CuO NPs) 100%
• Pulmonary Toxicity 100%
• Copper(II) Oxide 42%
• Oxidative Stress 28%
• Cytotoxicity 28%
• Immunotoxicity 28%
• Inflammatory Cytokines 14%
• Tumor Necrosis Factor-α 14%
• Expression Level 14%
• Dose Effect 14%
• High Concentration 14%
• Western Blot Analysis 14%
• Lactate 14%
• Glutathione Peroxidase (GSH-Px) 14%
• Heat Shock Proteins 14%
• Toxicological Biomarkers 14%
• Superoxide Dismutase 2 (SOD2) 14%
• Total Protein Content 14%
• Toxicity Mechanism 14%
• Catalase 14%
• Annexin A2 (ANXA2) 14%
• Polymorphonuclear Leukocytes 14%
• HSP47 14%
• PRDX2 14%
• Macrophage Inflammatory protein-2 14%
• 3-hydroxy-3-methylglutaryl-CoA Synthase 14%

Immunology and Microbiology

• Bronchoalveolar Lavage Fluid 100%
• Oxidative Stress 66%
• Cytotoxicity 66%
• Downregulation 33%
• Tumor Necrosis Factor 33%
• Inflammatory Cytokine 33%
• Superoxide 33%
• Western Blot 33%
• Upregulation 33%
• Heat Shock 33%
• Proteasome 33%
• Granulocyte 33%
• Macrophage Inflammatory Protein 2 33%