Pulsed laser activated cell sorting with three dimensional sheathless inertial focusing

Yue Chen; Aram J. Chung; Ting Hsiang Wu; Michael A. Teitell; Dino Di Carlo; Pei Yu Chiou

doi:10.1002/smll.201302885

Pulsed laser activated cell sorting with three dimensional sheathless inertial focusing

Yue Chen, Aram J. Chung, Ting Hsiang Wu, Michael A. Teitell, Dino Di Carlo, Pei Yu Chiou

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Abstract

A pulsed laser activated cell sorter (PLACS) integrated with 3D sheathless inertial focusing sorts cells with high purity at high-throughput using a single layer PDMS channel that can be easily fabricated at low cost. Sort purity of >90% is achieved at a throughput of 10 000 particles s^-1 without severe dilution effects from high volume sheath flows.

Original language	English
Pages (from-to)	1746-1751
Number of pages	6
Journal	Small
Volume	10
Issue number	9
DOIs	https://doi.org/10.1002/smll.201302885
Publication status	Published - 2014 May 14
Externally published	Yes

Keywords

cell sorting
inertial focusing
lab-on-a-chip devices
lasers
microfluidics

ASJC Scopus subject areas

Biotechnology
Biomaterials
Chemistry(all)
Materials Science(all)

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10.1002/smll.201302885

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abstract = "A pulsed laser activated cell sorter (PLACS) integrated with 3D sheathless inertial focusing sorts cells with high purity at high-throughput using a single layer PDMS channel that can be easily fabricated at low cost. Sort purity of >90% is achieved at a throughput of 10 000 particles s-1 without severe dilution effects from high volume sheath flows.",

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AU - Di Carlo, Dino

AU - Chiou, Pei Yu

PY - 2014/5/14

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KW - lab-on-a-chip devices

KW - lasers

KW - microfluidics

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Pulsed laser activated cell sorting with three dimensional sheathless inertial focusing

Abstract

Keywords

ASJC Scopus subject areas

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