Pyrrolic molecular rotors acting as viscosity sensors with high fluorescence contrast

Seung Chul Lee, Jeongyun Heo, Jong Wan Ryu, Chang Lyoul Lee, Sehoon Kim, Joon Sung Tae, Byung Ohk Rhee, Sang Wook Kim, O. Pil Kwon

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)


New pyrrolic viscosity sensors exhibit one order of magnitude higher fluorescence contrast compared to that of the conventional phenolic analogues due to the viscosity-sensitive rotation of the asymmetric pyrrole group and successfully demonstrate mapping of intracellular viscosity by fluorescence lifetime imaging microscopy.

Original languageEnglish
Pages (from-to)13695-13698
Number of pages4
JournalChemical Communications
Issue number94
Publication statusPublished - 2016
Externally publishedYes

Bibliographical note

Funding Information:
This work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (NRF- 2014R1A5A1009799, NRF-2009-0093826 and NRF-2016R1A2B401- 3003), by the GIST Research Institute (GRI) and the Intramural Research Program of KIST. The authors thank Dr Weon-Sik Chae, KBSI Daegu Center, for the FLIM experiments.

Publisher Copyright:
© 2016 The Royal Society of Chemistry.

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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