Pyrrolic molecular rotors acting as viscosity sensors with high fluorescence contrast

Seung Chul Lee; Jeongyun Heo; Jong Wan Ryu; Chang Lyoul Lee; Sehoon Kim; Joon Sung Tae; Byung Ohk Rhee; Sang Wook Kim; O. Pil Kwon

doi:10.1039/c6cc06521j

Pyrrolic molecular rotors acting as viscosity sensors with high fluorescence contrast

Seung Chul Lee, Jeongyun Heo, Jong Wan Ryu, Chang Lyoul Lee, Sehoon Kim, Joon Sung Tae, Byung Ohk Rhee, Sang Wook Kim, O. Pil Kwon

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

New pyrrolic viscosity sensors exhibit one order of magnitude higher fluorescence contrast compared to that of the conventional phenolic analogues due to the viscosity-sensitive rotation of the asymmetric pyrrole group and successfully demonstrate mapping of intracellular viscosity by fluorescence lifetime imaging microscopy.

Original language	English
Pages (from-to)	13695-13698
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	94
DOIs	https://doi.org/10.1039/c6cc06521j
Publication status	Published - 2016
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c6cc06521j

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title = "Pyrrolic molecular rotors acting as viscosity sensors with high fluorescence contrast",

abstract = "New pyrrolic viscosity sensors exhibit one order of magnitude higher fluorescence contrast compared to that of the conventional phenolic analogues due to the viscosity-sensitive rotation of the asymmetric pyrrole group and successfully demonstrate mapping of intracellular viscosity by fluorescence lifetime imaging microscopy.",

author = "Lee, {Seung Chul} and Jeongyun Heo and Ryu, {Jong Wan} and Lee, {Chang Lyoul} and Sehoon Kim and Tae, {Joon Sung} and Rhee, {Byung Ohk} and Kim, {Sang Wook} and Kwon, {O. Pil}",

note = "Funding Information: This work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (NRF- 2014R1A5A1009799, NRF-2009-0093826 and NRF-2016R1A2B401- 3003), by the GIST Research Institute (GRI) and the Intramural Research Program of KIST. The authors thank Dr Weon-Sik Chae, KBSI Daegu Center, for the FLIM experiments. Publisher Copyright: {\textcopyright} 2016 The Royal Society of Chemistry.",

year = "2016",

doi = "10.1039/c6cc06521j",

language = "English",

volume = "52",

pages = "13695--13698",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "94",

}

TY - JOUR

T1 - Pyrrolic molecular rotors acting as viscosity sensors with high fluorescence contrast

AU - Lee, Seung Chul

AU - Heo, Jeongyun

AU - Ryu, Jong Wan

AU - Lee, Chang Lyoul

AU - Kim, Sehoon

AU - Tae, Joon Sung

AU - Rhee, Byung Ohk

AU - Kim, Sang Wook

AU - Kwon, O. Pil

N1 - Funding Information: This work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (NRF- 2014R1A5A1009799, NRF-2009-0093826 and NRF-2016R1A2B401- 3003), by the GIST Research Institute (GRI) and the Intramural Research Program of KIST. The authors thank Dr Weon-Sik Chae, KBSI Daegu Center, for the FLIM experiments. Publisher Copyright: © 2016 The Royal Society of Chemistry.

PY - 2016

Y1 - 2016

N2 - New pyrrolic viscosity sensors exhibit one order of magnitude higher fluorescence contrast compared to that of the conventional phenolic analogues due to the viscosity-sensitive rotation of the asymmetric pyrrole group and successfully demonstrate mapping of intracellular viscosity by fluorescence lifetime imaging microscopy.

AB - New pyrrolic viscosity sensors exhibit one order of magnitude higher fluorescence contrast compared to that of the conventional phenolic analogues due to the viscosity-sensitive rotation of the asymmetric pyrrole group and successfully demonstrate mapping of intracellular viscosity by fluorescence lifetime imaging microscopy.

UR - http://www.scopus.com/inward/record.url?scp=84996761415&partnerID=8YFLogxK

U2 - 10.1039/c6cc06521j

DO - 10.1039/c6cc06521j

M3 - Article

AN - SCOPUS:84996761415

SN - 1359-7345

VL - 52

SP - 13695

EP - 13698

JO - Chemical Communications

JF - Chemical Communications

IS - 94

ER -

Pyrrolic molecular rotors acting as viscosity sensors with high fluorescence contrast

Abstract

ASJC Scopus subject areas

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