q-space upsampling using x-q space regularization

Geng Chen, Bin Dong, Yong Zhang, Dinggang Shen, Pew Thian Yap

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)


Acquisition time in diffusion MRI increases with the number of diffusion-weighted images that need to be acquired. Particularly in clinical settings, scan time is limited and only a sparse coverage of the vast q-space is possible. In this paper, we show how non-local self-similar information in the x-q space of diffusion MRI data can be harnessed for q-space upsampling. More specifically, we establish the relationships between signal measurements in x-q space using a patch matching mechanism that caters to unstructured data. We then encode these relationships in a graph and use it to regularize an inverse problem associated with recovering a high q-space resolution dataset from its low-resolution counterpart. Experimental results indicate that the high-resolution datasets reconstructed using the proposed method exhibit greater quality, both quantitatively and qualitatively, than those obtained using conventional methods, such as interpolation using spherical radial basis functions (SRBFs).

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention − MICCAI 2017 - 20th International Conference, Proceedings
EditorsMaxime Descoteaux, Simon Duchesne, Alfred Franz, Pierre Jannin, D. Louis Collins, Lena Maier-Hein
PublisherSpringer Verlag
Number of pages9
ISBN (Print)9783319661810
Publication statusPublished - 2017
Externally publishedYes
Event20th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2017 - Quebec City, Canada
Duration: 2017 Sept 112017 Sept 13

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume10433 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Other20th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2017
CityQuebec City

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)


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