Quality of life after endoscopic submucosal dissection for early gastric cancer: A prospective multicenter cohort study

Sang Gyun Kim; Seon Mi Ji; Na Rae Lee; Seung Hee Park; Ji Hye You; Il Ju Choi; Wan Sik Lee; Seun Ja Park; Jun Haeng Lee; Sang Yong Seol; Ji Hyun Kim; Chul Hyun Lim; Joo Young Cho; Gwang Ha Kim; Hoon Jai Chun; Yong Chan Lee; Hwoon Yong Jung; Jae J. Kim

doi:10.5009/gnl15549

Quality of life after endoscopic submucosal dissection for early gastric cancer: A prospective multicenter cohort study

Sang Gyun Kim, Seon Mi Ji, Na Rae Lee, Seung Hee Park, Ji Hye You, Il Ju Choi, Wan Sik Lee, Seun Ja Park, Jun Haeng Lee, Sang Yong Seol, Ji Hyun Kim, Chul Hyun Lim, Joo Young Cho, Gwang Ha Kim, Hoon Jai Chun, Yong Chan Lee, Hwoon Yong Jung, Jae J. Kim

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

Background/Aims: Endoscopic submucosal dissection (ESD) has been an established treatment for indicated early gastric cancer (EGC) without deterioration of quality of life (QOL) compared with surgical resection. The aim of this study was to evaluate long-term QOL in patients undergoing ESD for EGC. Methods: Patients scheduled to undergo curative ESD for EGC were prospectively enrolled from 12 institutions between May 2010 and December 2011. Assessments of QOL with Korean versions of the European Organization for Research and Treatment of Cancer (EORTC) QOL questionnaire-core (QLQ-C30) and a gastric cancer-specific questionnaire (STO22) were performed at baseline and at 7 days, 3 months, and 6 months after ESD. Results: A total of 666 subjects were assessed for QLQ-C30 and QLQ-STO22. The mean QLQ-C30 score was 69.5 at baseline, 68.8 at 7 days, 73.1 at 3 months, and 73.2 at 6 months. The global health status on the EORTC QLQ-C30 was significantly improved after 3 and 6 months (p=0.0003 and p<0.0001, respectively). The QLQ-C30 and STO22 scores were not significantly different, or they only slightly deteriorated between before and immediately after ESD, but they were significantly improved after 3 and 6 months (p<0.05). Conclusions: QOL did not deteriorate immediately after ESD, and it improved more significantly at up to 6 months in patients who underwent curative ESD for EGC without significant complications.

Original language	English
Pages (from-to)	87-92
Number of pages	6
Journal	Gut and liver
Volume	11
Issue number	1
DOIs	https://doi.org/10.5009/gnl15549
Publication status	Published - 2017 Jan
Externally published	Yes

Keywords

Early gastric cancer
Endoscopic submucosal dissection
Quality of life

ASJC Scopus subject areas

Hepatology
Gastroenterology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.5009/gnl15549

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Kim, S. G., Ji, S. M., Lee, N. R., Park, S. H., You, J. H., Choi, I. J., Lee, W. S., Park, S. J., Lee, J. H., Seol, S. Y., Kim, J. H., Lim, C. H., Cho, J. Y., Kim, G. H., Chun, H. J., Lee, Y. C., Jung, H. Y., & Kim, J. J. (2017). Quality of life after endoscopic submucosal dissection for early gastric cancer: A prospective multicenter cohort study. Gut and liver, 11(1), 87-92. https://doi.org/10.5009/gnl15549

Kim, SG, Ji, SM, Lee, NR, Park, SH, You, JH, Choi, IJ, Lee, WS, Park, SJ, Lee, JH, Seol, SY, Kim, JH, Lim, CH, Cho, JY, Kim, GH, Chun, HJ, Lee, YC, Jung, HY & Kim, JJ 2017, 'Quality of life after endoscopic submucosal dissection for early gastric cancer: A prospective multicenter cohort study', Gut and liver, vol. 11, no. 1, pp. 87-92. https://doi.org/10.5009/gnl15549

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title = "Quality of life after endoscopic submucosal dissection for early gastric cancer: A prospective multicenter cohort study",

abstract = "Background/Aims: Endoscopic submucosal dissection (ESD) has been an established treatment for indicated early gastric cancer (EGC) without deterioration of quality of life (QOL) compared with surgical resection. The aim of this study was to evaluate long-term QOL in patients undergoing ESD for EGC. Methods: Patients scheduled to undergo curative ESD for EGC were prospectively enrolled from 12 institutions between May 2010 and December 2011. Assessments of QOL with Korean versions of the European Organization for Research and Treatment of Cancer (EORTC) QOL questionnaire-core (QLQ-C30) and a gastric cancer-specific questionnaire (STO22) were performed at baseline and at 7 days, 3 months, and 6 months after ESD. Results: A total of 666 subjects were assessed for QLQ-C30 and QLQ-STO22. The mean QLQ-C30 score was 69.5 at baseline, 68.8 at 7 days, 73.1 at 3 months, and 73.2 at 6 months. The global health status on the EORTC QLQ-C30 was significantly improved after 3 and 6 months (p=0.0003 and p<0.0001, respectively). The QLQ-C30 and STO22 scores were not significantly different, or they only slightly deteriorated between before and immediately after ESD, but they were significantly improved after 3 and 6 months (p<0.05). Conclusions: QOL did not deteriorate immediately after ESD, and it improved more significantly at up to 6 months in patients who underwent curative ESD for EGC without significant complications.",

keywords = "Early gastric cancer, Endoscopic submucosal dissection, Quality of life",

author = "Kim, {Sang Gyun} and Ji, {Seon Mi} and Lee, {Na Rae} and Park, {Seung Hee} and You, {Ji Hye} and Choi, {Il Ju} and Lee, {Wan Sik} and Park, {Seun Ja} and Lee, {Jun Haeng} and Seol, {Sang Yong} and Kim, {Ji Hyun} and Lim, {Chul Hyun} and Cho, {Joo Young} and Kim, {Gwang Ha} and Chun, {Hoon Jai} and Lee, {Yong Chan} and Jung, {Hwoon Yong} and Kim, {Jae J.}",

year = "2017",

month = jan,

doi = "10.5009/gnl15549",

language = "English",

volume = "11",

pages = "87--92",

journal = "Gut and Liver",

issn = "1976-2283",

publisher = "Joe Bok Chung",

number = "1",

}

TY - JOUR

T1 - Quality of life after endoscopic submucosal dissection for early gastric cancer

T2 - A prospective multicenter cohort study

AU - Kim, Sang Gyun

AU - Ji, Seon Mi

AU - Lee, Na Rae

AU - Park, Seung Hee

AU - You, Ji Hye

AU - Choi, Il Ju

AU - Lee, Wan Sik

AU - Park, Seun Ja

AU - Lee, Jun Haeng

AU - Seol, Sang Yong

AU - Kim, Ji Hyun

AU - Lim, Chul Hyun

AU - Cho, Joo Young

AU - Kim, Gwang Ha

AU - Chun, Hoon Jai

AU - Lee, Yong Chan

AU - Jung, Hwoon Yong

AU - Kim, Jae J.

PY - 2017/1

Y1 - 2017/1

N2 - Background/Aims: Endoscopic submucosal dissection (ESD) has been an established treatment for indicated early gastric cancer (EGC) without deterioration of quality of life (QOL) compared with surgical resection. The aim of this study was to evaluate long-term QOL in patients undergoing ESD for EGC. Methods: Patients scheduled to undergo curative ESD for EGC were prospectively enrolled from 12 institutions between May 2010 and December 2011. Assessments of QOL with Korean versions of the European Organization for Research and Treatment of Cancer (EORTC) QOL questionnaire-core (QLQ-C30) and a gastric cancer-specific questionnaire (STO22) were performed at baseline and at 7 days, 3 months, and 6 months after ESD. Results: A total of 666 subjects were assessed for QLQ-C30 and QLQ-STO22. The mean QLQ-C30 score was 69.5 at baseline, 68.8 at 7 days, 73.1 at 3 months, and 73.2 at 6 months. The global health status on the EORTC QLQ-C30 was significantly improved after 3 and 6 months (p=0.0003 and p<0.0001, respectively). The QLQ-C30 and STO22 scores were not significantly different, or they only slightly deteriorated between before and immediately after ESD, but they were significantly improved after 3 and 6 months (p<0.05). Conclusions: QOL did not deteriorate immediately after ESD, and it improved more significantly at up to 6 months in patients who underwent curative ESD for EGC without significant complications.

AB - Background/Aims: Endoscopic submucosal dissection (ESD) has been an established treatment for indicated early gastric cancer (EGC) without deterioration of quality of life (QOL) compared with surgical resection. The aim of this study was to evaluate long-term QOL in patients undergoing ESD for EGC. Methods: Patients scheduled to undergo curative ESD for EGC were prospectively enrolled from 12 institutions between May 2010 and December 2011. Assessments of QOL with Korean versions of the European Organization for Research and Treatment of Cancer (EORTC) QOL questionnaire-core (QLQ-C30) and a gastric cancer-specific questionnaire (STO22) were performed at baseline and at 7 days, 3 months, and 6 months after ESD. Results: A total of 666 subjects were assessed for QLQ-C30 and QLQ-STO22. The mean QLQ-C30 score was 69.5 at baseline, 68.8 at 7 days, 73.1 at 3 months, and 73.2 at 6 months. The global health status on the EORTC QLQ-C30 was significantly improved after 3 and 6 months (p=0.0003 and p<0.0001, respectively). The QLQ-C30 and STO22 scores were not significantly different, or they only slightly deteriorated between before and immediately after ESD, but they were significantly improved after 3 and 6 months (p<0.05). Conclusions: QOL did not deteriorate immediately after ESD, and it improved more significantly at up to 6 months in patients who underwent curative ESD for EGC without significant complications.

KW - Early gastric cancer

KW - Endoscopic submucosal dissection

KW - Quality of life

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U2 - 10.5009/gnl15549

DO - 10.5009/gnl15549

M3 - Article

C2 - 27282267

AN - SCOPUS:85012884099

SN - 1976-2283

VL - 11

SP - 87

EP - 92

JO - Gut and Liver

JF - Gut and Liver

IS - 1

ER -

Quality of life after endoscopic submucosal dissection for early gastric cancer: A prospective multicenter cohort study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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