@inproceedings{24dc277ec5d3482085f3ccd48c9e901a,
title = "Radiation effect on 3D micro vascular network in in vitro microfluidic chip",
abstract = "To demonstrate a radiation effect on vasculature, we designed 3D in vitro micro vascular system. We used soft-lithography method to fabricate in vitro microfluidic chip which was composed of two media channels and three gel channels. We cultured human umbilical vein endothelial cells(HUVECs) to make vasculature. To form a vasculature, fibrin gel was used as extracellular matrix to support HUVECs. After embedding, HUVECs were exposed to radiation on day 0 or 4. After irradiation, we analyzed structure of vasculature and measured gene expression. The results demonstrate a difference radioresistance between early stage of vasculature and mature stage of vasculature.",
keywords = "3D vasculature, In vitro microfluidic chip, Radiation",
author = "Choi, {Dong Hee} and Na, {Kyu Hwan} and Hyunho Kim and Jung, {Yong Hun} and Kim, {Chun Ho} and Seok Chung",
year = "2020",
month = jan,
day = "1",
language = "English",
series = "21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017",
publisher = "Chemical and Biological Microsystems Society",
pages = "60--61",
booktitle = "21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017",
note = "21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 ; Conference date: 22-10-2017 Through 26-10-2017",
}