Abstract
Biotin-disulfide-coumarin conjugates are designed and synthesized as novel fluorescent sensors for cancer targeted intracellular thiol imaging in living organisms. In vitro experiments disclose that probe 6 is preferentially taken up by biotin receptor-positive A549 tumor cells through receptor mediated endocytosis.
Original language | English |
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Pages (from-to) | 3044-3047 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 50 |
Issue number | 23 |
DOIs | |
Publication status | Published - 2014 Feb 20 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry