Abstract
In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received " sham" feedback. This " dynamic" characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.
| Original language | English |
|---|---|
| Pages (from-to) | 347-354 |
| Number of pages | 8 |
| Journal | Neuroscience Research |
| Volume | 72 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2012 Apr |
Bibliographical note
Funding Information:This work was supported by the World Class University (WCU) program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education, Science and Technology ( R31-10008 ) and the Basic Science Research Program , NRF grant of Korea ( 2011-0004794 ). These sponsors had no involvement in study design, data collection, analysis or interpretation of data, manuscript preparation, or the decision to submit for publication.
Keywords
- Auditory attention
- Effective connectivity
- Functional MRI (fMRI)
- Granger causality
- Neurofeedback
- Real-time fMRI
ASJC Scopus subject areas
- General Neuroscience