Real-time fMRI-based neurofeedback reinforces causality of attention networks

Jong Hwan Lee; Junghoe Kim; Seung Schik Yoo

doi:10.1016/j.neures.2012.01.002

Real-time fMRI-based neurofeedback reinforces causality of attention networks

Jong Hwan Lee^*
, Junghoe Kim
, Seung Schik Yoo

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

Abstract

In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received " sham" feedback. This " dynamic" characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.

Original language	English
Pages (from-to)	347-354
Number of pages	8
Journal	Neuroscience Research
Volume	72
Issue number	4
DOIs	https://doi.org/10.1016/j.neures.2012.01.002
Publication status	Published - 2012 Apr

Bibliographical note

Funding Information:
This work was supported by the World Class University (WCU) program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education, Science and Technology ( R31-10008 ) and the Basic Science Research Program , NRF grant of Korea ( 2011-0004794 ). These sponsors had no involvement in study design, data collection, analysis or interpretation of data, manuscript preparation, or the decision to submit for publication.

Keywords

Auditory attention
Effective connectivity
Functional MRI (fMRI)
Granger causality
Neurofeedback
Real-time fMRI

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.neures.2012.01.002

Cite this

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title = "Real-time fMRI-based neurofeedback reinforces causality of attention networks",

abstract = "In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received {"} sham{"} feedback. This {"} dynamic{"} characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.",

keywords = "Auditory attention, Effective connectivity, Functional MRI (fMRI), Granger causality, Neurofeedback, Real-time fMRI",

author = "Lee, \{Jong Hwan\} and Junghoe Kim and Yoo, \{Seung Schik\}",

note = "Funding Information: This work was supported by the World Class University (WCU) program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education, Science and Technology ( R31-10008 ) and the Basic Science Research Program , NRF grant of Korea ( 2011-0004794 ). These sponsors had no involvement in study design, data collection, analysis or interpretation of data, manuscript preparation, or the decision to submit for publication.",

year = "2012",

month = apr,

doi = "10.1016/j.neures.2012.01.002",

language = "English",

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AU - Lee, Jong Hwan

AU - Kim, Junghoe

AU - Yoo, Seung Schik

N1 - Funding Information: This work was supported by the World Class University (WCU) program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education, Science and Technology ( R31-10008 ) and the Basic Science Research Program , NRF grant of Korea ( 2011-0004794 ). These sponsors had no involvement in study design, data collection, analysis or interpretation of data, manuscript preparation, or the decision to submit for publication.

PY - 2012/4

Y1 - 2012/4

N2 - In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received " sham" feedback. This " dynamic" characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.

AB - In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received " sham" feedback. This " dynamic" characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.

KW - Auditory attention

KW - Effective connectivity

KW - Functional MRI (fMRI)

KW - Granger causality

KW - Neurofeedback

KW - Real-time fMRI

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DO - 10.1016/j.neures.2012.01.002

M3 - Article

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AN - SCOPUS:84862779855

SN - 0168-0102

VL - 72

SP - 347

EP - 354

JO - Neuroscience Research

JF - Neuroscience Research

IS - 4

ER -

Real-time fMRI-based neurofeedback reinforces causality of attention networks

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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