Real time OFF-ON monitoring of gluthathione (GSH) in living cell

Jae Hong Lee; Amit Sharma; Joo Hee Jang; Weon Sup Shin; Joung Hae Lee; Jong Seung Kim

doi:10.1007/s10847-015-0486-y

Real time OFF-ON monitoring of gluthathione (GSH) in living cell

Jae Hong Lee
, Amit Sharma
, Joo Hee Jang
, Weon Sup Shin
, Joung Hae Lee
, Jong Seung Kim

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

A simple chemodosimetric probe (1) is reported which detects Glutathione (GSH) selectively over other relevant biological species under physiological condition by turning on its fluorescence through the imine hydrolysis reaction. The probe has also been used for imaging of GSH in the live cells by confocal microscopy. Graphical Abstract This report discloses pyrene-based chemodosimetric probe which exhibit a selective response toward Glutathione (GSH) over other biological thiols and was successfully applied to the imaging of GSH in living cells.

Original language	English
Pages (from-to)	117-122
Number of pages	6
Journal	Journal of Inclusion Phenomena and Macrocyclic Chemistry
Volume	82
Issue number	1
DOIs	https://doi.org/10.1007/s10847-015-0486-y
Publication status	Published - 2015 Jun

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media Dordrecht 2015.

Keywords

Chemodosimetric
Fluorescence
Glutathione (GSH)
Imine-hydrolysis

ASJC Scopus subject areas

Food Science
General Chemistry
Condensed Matter Physics

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10.1007/s10847-015-0486-y

Cite this

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title = "Real time OFF-ON monitoring of gluthathione (GSH) in living cell",

abstract = "A simple chemodosimetric probe (1) is reported which detects Glutathione (GSH) selectively over other relevant biological species under physiological condition by turning on its fluorescence through the imine hydrolysis reaction. The probe has also been used for imaging of GSH in the live cells by confocal microscopy. Graphical Abstract This report discloses pyrene-based chemodosimetric probe which exhibit a selective response toward Glutathione (GSH) over other biological thiols and was successfully applied to the imaging of GSH in living cells.",

keywords = "Chemodosimetric, Fluorescence, Glutathione (GSH), Imine-hydrolysis",

author = "Lee, \{Jae Hong\} and Amit Sharma and Jang, \{Joo Hee\} and Shin, \{Weon Sup\} and Lee, \{Joung Hae\} and Kim, \{Jong Seung\}",

note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media Dordrecht 2015.",

year = "2015",

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doi = "10.1007/s10847-015-0486-y",

language = "English",

volume = "82",

pages = "117--122",

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T1 - Real time OFF-ON monitoring of gluthathione (GSH) in living cell

AU - Lee, Jae Hong

AU - Sharma, Amit

AU - Jang, Joo Hee

AU - Shin, Weon Sup

AU - Lee, Joung Hae

AU - Kim, Jong Seung

N1 - Publisher Copyright: © Springer Science+Business Media Dordrecht 2015.

PY - 2015/6

Y1 - 2015/6

N2 - A simple chemodosimetric probe (1) is reported which detects Glutathione (GSH) selectively over other relevant biological species under physiological condition by turning on its fluorescence through the imine hydrolysis reaction. The probe has also been used for imaging of GSH in the live cells by confocal microscopy. Graphical Abstract This report discloses pyrene-based chemodosimetric probe which exhibit a selective response toward Glutathione (GSH) over other biological thiols and was successfully applied to the imaging of GSH in living cells.

AB - A simple chemodosimetric probe (1) is reported which detects Glutathione (GSH) selectively over other relevant biological species under physiological condition by turning on its fluorescence through the imine hydrolysis reaction. The probe has also been used for imaging of GSH in the live cells by confocal microscopy. Graphical Abstract This report discloses pyrene-based chemodosimetric probe which exhibit a selective response toward Glutathione (GSH) over other biological thiols and was successfully applied to the imaging of GSH in living cells.

KW - Chemodosimetric

KW - Fluorescence

KW - Glutathione (GSH)

KW - Imine-hydrolysis

UR - https://www.scopus.com/pages/publications/84944387280

U2 - 10.1007/s10847-015-0486-y

DO - 10.1007/s10847-015-0486-y

M3 - Article

AN - SCOPUS:84944387280

SN - 0923-0750

VL - 82

SP - 117

EP - 122

JO - Journal of Inclusion Phenomena and Macrocyclic Chemistry

JF - Journal of Inclusion Phenomena and Macrocyclic Chemistry

IS - 1

ER -

Real time OFF-ON monitoring of gluthathione (GSH) in living cell

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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