Abstract
In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.
| Original language | English |
|---|---|
| Pages (from-to) | 539-557 |
| Number of pages | 19 |
| Journal | Anti-Cancer Agents in Medicinal Chemistry |
| Volume | 16 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2016 May 1 |
Bibliographical note
Funding Information:This work was supported by a grant of Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2103R1A1A2013610, 2014R1A2A2A01005455 and 2012M3A9C1053532), Republic of Korea
Publisher Copyright:
© 2016 Bentham Science Publishers.
Keywords
- Anticancer agents
- Azepane scaffold
- Chemotherapeutics
- Histone deacetylases
- Hormone modulators
- Kinase inhibitors
- Phototherapeutic agents
- Tubulin inhibitors
ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology
- Cancer Research
