Recent advances in anticancer chemotherapeutics based upon azepine scaffold

Sarbjit Singh, Jail Goo, Veeraswamy Gajulapati, Tong Shin Chang, Kyeong Lee, Yongseok Choi

    Research output: Contribution to journalReview articlepeer-review

    12 Citations (Scopus)

    Abstract

    In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.

    Original languageEnglish
    Pages (from-to)539-557
    Number of pages19
    JournalAnti-Cancer Agents in Medicinal Chemistry
    Volume16
    Issue number5
    DOIs
    Publication statusPublished - 2016 May 1

    Bibliographical note

    Publisher Copyright:
    © 2016 Bentham Science Publishers.

    Keywords

    • Anticancer agents
    • Azepane scaffold
    • Chemotherapeutics
    • Histone deacetylases
    • Hormone modulators
    • Kinase inhibitors
    • Phototherapeutic agents
    • Tubulin inhibitors

    ASJC Scopus subject areas

    • Molecular Medicine
    • Pharmacology
    • Cancer Research

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