Recent advances in anticancer chemotherapeutics based upon azepine scaffold

Sarbjit Singh, Jail Goo, Veeraswamy Gajulapati, Tong Shin Chang, Kyeong Lee, Yongseok Choi

Research output: Contribution to journalReview articlepeer-review

12 Citations (Scopus)


In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.

Original languageEnglish
Pages (from-to)539-557
Number of pages19
JournalAnti-Cancer Agents in Medicinal Chemistry
Issue number5
Publication statusPublished - 2016 May 1

Bibliographical note

Funding Information:
This work was supported by a grant of Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2103R1A1A2013610, 2014R1A2A2A01005455 and 2012M3A9C1053532), Republic of Korea

Publisher Copyright:
© 2016 Bentham Science Publishers.


  • Anticancer agents
  • Azepane scaffold
  • Chemotherapeutics
  • Histone deacetylases
  • Hormone modulators
  • Kinase inhibitors
  • Phototherapeutic agents
  • Tubulin inhibitors

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology
  • Cancer Research


Dive into the research topics of 'Recent advances in anticancer chemotherapeutics based upon azepine scaffold'. Together they form a unique fingerprint.

Cite this