Recent Progress in the Chemistry of Pyridazinones for Functional Group Transformations

Seohyun Kang, Hyun Kyung Moon, Yong Jin Yoon, Hyo Jae Yoon

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

While N-hetereocycles have received significant attention in organic synthesis and other research fields, the chemistry of pyridazine, a six-membered aromatic ring with two adjacent nitrogen atoms, and its derivatives has been relatively little understood. This Synopsis describes recent progress made in the synthesis of pyridazine derivatives - particularly, pyridazin-3(2H)-ones - and their utility as efficient and recyclable functional group carriers for various important organic reactions.

Original languageEnglish
Pages (from-to)1-11
Number of pages11
JournalJournal of Organic Chemistry
Volume83
Issue number1
DOIs
Publication statusPublished - 2018 Jan 5

Bibliographical note

Funding Information:
H.J.Y. acknowledges support from the Future Research Grant at Korea University, and National Research Foundation of Korea (NRF-2017M3A7B8064518). Y.-J.Y. sincerely thanks all his former co-workers involved in the projects related to pyridazine chemistry and Prof. L. B. Townsend, Emeritus Professor of Medicinal Chemistry at the University of Michigan, who motivated him to dedicate his entire carrier to the exploration of pyridazine chemistry.

Publisher Copyright:
© 2017 American Chemical Society.

ASJC Scopus subject areas

  • Organic Chemistry

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