Recent studies on anti-aging compounds with Saccharomyces cerevisiae as a model organism

Gulperi Yalcin; Cheol Koo Lee

doi:10.1016/j.tma.2019.10.001

Recent studies on anti-aging compounds with Saccharomyces cerevisiae as a model organism

Gulperi Yalcin, Cheol Koo Lee

Department of Biotechnology

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

Abstract

Extension of lifespan and amelioration of aging-associated phenotypes have been targets of many studies. Some of the established methods of increasing lifespan including dietary restriction and genetic manipulation are difficult to apply to humans, and their side effects are hard to predict. For that reason, it is important to discover compounds that can mimic the anti-aging actions or induce lifespan extension through different metabolisms within the cell. Here we summarize the recent studies to test various types of compounds and materials using budding yeast that show potential anti-aging effects.

Original language	English
Pages (from-to)	109-115
Number of pages	7
Journal	Translational Medicine of Aging
Volume	3
DOIs	https://doi.org/10.1016/j.tma.2019.10.001
Publication status	Published - 2019

Keywords

Anti-aging agent
Budding yeast
Chronological lifespan
Lifespan extension
Replicative lifespan

ASJC Scopus subject areas

Geriatrics and Gerontology
Clinical Neurology
Ageing
Physiology
Cell Biology

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10.1016/j.tma.2019.10.001

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abstract = "Extension of lifespan and amelioration of aging-associated phenotypes have been targets of many studies. Some of the established methods of increasing lifespan including dietary restriction and genetic manipulation are difficult to apply to humans, and their side effects are hard to predict. For that reason, it is important to discover compounds that can mimic the anti-aging actions or induce lifespan extension through different metabolisms within the cell. Here we summarize the recent studies to test various types of compounds and materials using budding yeast that show potential anti-aging effects.",

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AU - Yalcin, Gulperi

AU - Lee, Cheol Koo

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AB - Extension of lifespan and amelioration of aging-associated phenotypes have been targets of many studies. Some of the established methods of increasing lifespan including dietary restriction and genetic manipulation are difficult to apply to humans, and their side effects are hard to predict. For that reason, it is important to discover compounds that can mimic the anti-aging actions or induce lifespan extension through different metabolisms within the cell. Here we summarize the recent studies to test various types of compounds and materials using budding yeast that show potential anti-aging effects.

KW - Anti-aging agent

KW - Budding yeast

KW - Chronological lifespan

KW - Lifespan extension

KW - Replicative lifespan

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DO - 10.1016/j.tma.2019.10.001

M3 - Review article

AN - SCOPUS:85081095805

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JO - Translational Medicine of Aging

JF - Translational Medicine of Aging

ER -

Recent studies on anti-aging compounds with Saccharomyces cerevisiae as a model organism

Abstract

Keywords

ASJC Scopus subject areas

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