Recurrence rate of herpes zoster during the previous decade

Background: Herpes zoster recurrence, reported to be 1-5% globally, is thought to be more frequent in immunocompromised and older individuals. Data on the recurrence rate in Korea are very rare. Objective: This study assessed the rate and affecting factors of herpes zoster recurrence, in a Korean population. Methods: From May, 2001 to May, 2011, 2210 patients with confirmed herpes zoster episodes were enrolled. Recurrence episodes and affecting factors of herpes zoster were confirmed using telephone question and medical record review. Results: The overall recurrence rate of herpes zoster was 2.31%. Recurrences were significantly more likely in persons with zoster-associated pain of 30 days or longer, at the initial episode, and in immunocmpromised patients. Women and anyone aged between 50 and 70 years, at the index episode, had a greater likelihood of recurrence. Conclusion: Recurrence of herpes zoster is more common in women and is associated with pain duration and immune status.