Recurrent Hepatocellular Carcinoma: Percutaneous Radiofrequency Ablation after Hepatectomy

Dongil Choi, Hyo K. Lim, Min Ju Kim, Sung Hoon Lee, Seung Hoon Kim, Won Jae Lee, Jae Hoon Lim, Jae Won Joh, Yong Il Kim

Research output: Contribution to journalArticlepeer-review

53 Citations (Scopus)


PURPOSE: To evaluate the therapeutic efficacy and safety of percutaneous radiofrequency (RF) ablation for recurrent hepatocellular carcinoma (HCC) in the liver after hepatectomy. MATERIALS AND METHODS: Forty-five patients with 53 recurrent HCC tumors in the liver underwent percutaneous RF ablation with ultrasonographic guidance. All patients had a history of hepatic resection for HCC. The mean diameter of recurrent tumors was 2.1 cm (range, 0.8-4.0 cm). All patients were followed up for at least 10 months after ablation (range, 10-40 months; mean, 23 months). Therapeutic efficacy and complications were evaluated with multiphase helical computed tomography (CT) at regular follow-up visits. Overall and disease-free survival rates were calculated. RESULTS: At follow-up CT after initial RF ablation, 11 (21%) of 53 ablated HCC tumor sites showed residual tumor or local tumor progression. After additional RF ablation, complete ablation of 46 (87%) of 53 tumors was attained. Also at initial follow-up CT, before either additional RF ablation or other treatment was performed, 21 (47%) of 45 patients were found to have 41 new HCC tumors at other liver sites. Of these, nine tumors in eight patients were treatable with a second application of RF ablation. Overall survival rates at 1, 2, and 3 years were 82%, 72%, and 54%, respectively. No deaths or complications requiring further treatment occurred as a result of RF ablation. CONCLUSION: Percutaneous RF ablation is an effective and safe method for treating recurrent HCC in the liver after hepatectomy, with a good overall patient survival rate.

Original languageEnglish
Pages (from-to)135-141
Number of pages7
Issue number1
Publication statusPublished - 2004 Jan
Externally publishedYes


  • Liver neoplasms, therapy
  • Liver, interventional procedures
  • Liver, surgery
  • Radiofrequency (RF) ablation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Recurrent Hepatocellular Carcinoma: Percutaneous Radiofrequency Ablation after Hepatectomy'. Together they form a unique fingerprint.

Cite this