Relationship between plasma adiponectin levels and the metabolic syndrome among Korean people

Seon Mee Kim, Kyung Hwan Cho, Hye Soon Park

    Research output: Contribution to journalArticlepeer-review

    24 Citations (Scopus)


    We investigated the relationship between plasma adiponectin levels and the parameters of the metabolic syndrome among Koreans. In 67 male and 115 female subjects, aged from 30 to 70 years, plasma adiponectin levels were positively correlated with HDL-cholesterol levels (r = 0.295, P<0.001), but negatively correlated with waist circumference (r = -0.140, P = 0.020), triglycerides (r = -0.174, P = 0.021), fasting plasma glucose (r = -0.159, P = 0.036), fasting plasma insulin (r = -0.172, P = 0.023) and HOMA-IR (r = -0.182, P<0.001), after adjustment for age, sex, and BMI. Stepwise multiple regression analyses revealed that HDL-cholesterol, sex, and HOMA-IR were the independent associated factors for plasma adiponectin levels. Multiple logistic analyses demonstrated that HOMA-IR, BMI, and age were the predominant independent factors associated with the metabolic syndrome, while plasma adiponectin levels exhibited a protective effect against the presence of the metabolic syndrome according to both NCEP ATP III criteria and IDF definition. Hypoadiponectinemia is associated with the phenotype of the metabolic syndrome as well as components of the metabolic syndrome.

    Original languageEnglish
    Pages (from-to)247-254
    Number of pages8
    JournalEndocrine Journal
    Issue number2
    Publication statusPublished - 2006


    • Adiponectin
    • Korean
    • Metabolic syndrome

    ASJC Scopus subject areas

    • Endocrinology, Diabetes and Metabolism
    • Endocrinology


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