Research progress of M13 bacteriophage-based biosensors

Jong Sik Moon, Eun Jung Choi, Na Na Jeong, Jong Ryeul Sohn, Dong Wook Han, Jin Woo Oh

    Research output: Contribution to journalReview articlepeer-review

    38 Citations (Scopus)

    Abstract

    Recently, new virus-based sensor systems that operate on M13 bacteriophage infrastructure have attracted considerable attention. These systems can detect a range of chemicals with excellent sensitivity and selectivity. Filaments consistent with M13 bacteriophages can be ordered by highly established forms of self-assembly. This allows M13 bacteriophages to build a homogeneous distribution and infiltrate the network structure of nanostructures under mild conditions. Phage display, involving the genetic engineering of M13 bacteriophages, is another strong feature of the M13 bacteriophage as a functional building block. The numerous genetic modification possibilities of M13 bacteriophages are clearly the key features, and far more applications are envisaged. This paper reviews the recent progress in the application of the M13 bacteriophage self-assembly structures through to sensor systems and discusses future M13 bacteriophage technology.

    Original languageEnglish
    Article number1448
    JournalNanomaterials
    Volume9
    Issue number10
    DOIs
    Publication statusPublished - 2019 Oct

    Bibliographical note

    Publisher Copyright:
    © 2019 by the authors. Licensee MDPI, Basel, Switzerland.

    Keywords

    • Biosensor
    • Color sensor
    • M13 bacteriophage
    • Phage display
    • Virus

    ASJC Scopus subject areas

    • General Chemical Engineering
    • General Materials Science

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