Abstract
Recently, new virus-based sensor systems that operate on M13 bacteriophage infrastructure have attracted considerable attention. These systems can detect a range of chemicals with excellent sensitivity and selectivity. Filaments consistent with M13 bacteriophages can be ordered by highly established forms of self-assembly. This allows M13 bacteriophages to build a homogeneous distribution and infiltrate the network structure of nanostructures under mild conditions. Phage display, involving the genetic engineering of M13 bacteriophages, is another strong feature of the M13 bacteriophage as a functional building block. The numerous genetic modification possibilities of M13 bacteriophages are clearly the key features, and far more applications are envisaged. This paper reviews the recent progress in the application of the M13 bacteriophage self-assembly structures through to sensor systems and discusses future M13 bacteriophage technology.
Original language | English |
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Article number | 1448 |
Journal | Nanomaterials |
Volume | 9 |
Issue number | 10 |
DOIs | |
Publication status | Published - 2019 Oct |
Bibliographical note
Funding Information:Funding: This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health and Welfare, Korea (HI17C1662). This work was also supported by the National Research Foundation of Korea (NRF) Grant funded by the Korean Government (MOE) (No. NRF-2016R1A6A3A11931113 and NRF-2017M3A9E4048170).
Funding Information:
This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health and Welfare, Korea (HI17C1662). This work was also supported by the National Research Foundation of Korea (NRF) Grant funded by the Korean Government (MOE) (No. NRF-2016R1A6A3A11931113 and NRF-2017M3A9E4048170).
Publisher Copyright:
© 2019 by the authors. Licensee MDPI, Basel, Switzerland.
Keywords
- Biosensor
- Color sensor
- M13 bacteriophage
- Phage display
- Virus
ASJC Scopus subject areas
- Chemical Engineering(all)
- Materials Science(all)