Response to chloroquine of Plasmodium vivax among South Korean soldiers

C. S. Lim, Y. K. Kim, K. N. Lee, M. J. Kim, K. H. Kim, D. S. Kim, D. Strickman

    Research output: Contribution to journalArticlepeer-review

    14 Citations (Scopus)

    Abstract

    The response to standard chloroquine treatment was evaluated, by microscopical examination of blood-smears, among 81 soldiers diagnosed with Plasmodium vivax malaria in South Korea in 1996. The smears were prepared pre-treatment and 3, 14 and 28 days after starting chemotherapy. Parasitaemias were determined after staining the smears with Giemsa's stain. Blood samples from the patients who were not smear-negative by day 3 were carefully checked for parasites, by staining smears with Acridine Orange and by a PCR-based assay. Only two of the patients appeared to be parasitaemic on day 14 and were therefore considered treatment failures. Although both were apparently cured after additional therapy with the same regimen, one had a recurrence 8 months later. Most cases of recent, resurgent malaria in South Korea therefore appear to sensitive to chloroquine.

    Original languageEnglish
    Pages (from-to)565-568
    Number of pages4
    JournalAnnals of Tropical Medicine and Parasitology
    Volume93
    Issue number6
    DOIs
    Publication statusPublished - 1999

    ASJC Scopus subject areas

    • Parasitology
    • Infectious Diseases

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