Review of cohort studies for mood disorders

Mood Disorders Cohort Research Consortium (MDCRC) Group

Research output: Contribution to journalReview articlepeer-review

7 Citations (Scopus)


This paper aimed to review currently available cohort studies of subjects with mood disorders such as major depressive disorder (MDD) and bipolar disorder (BD). Using the PubMed and KoreaMed databases, we reviewed eight major cohort studies. Most studies recruited participants with MDD and BD separately, so direct comparison of factors associated with diagnostic changes was difficult. Regular and frequent follow-up evaluations utilizing objective mood ratings and standardized evaluation methods in a naturalistic fashion are necessary to determine detailed clinical courses of mood disorders. Further, biological samples should also be collected to incorporate clinical findings in the development of new diagnostic and therapeutic approaches. An innovative cohort study that can serve as a platform for translational research for treatment and prevention of mood disorders is critical in determining clinical, psychosocial, neurobiological and genetic factors associated with long-term courses and consequences of mood disorders in Korean patients.

Original languageEnglish
Pages (from-to)265-276
Number of pages12
JournalPsychiatry Investigation
Issue number3
Publication statusPublished - 2016 May

Bibliographical note

Publisher Copyright:
© 2016 Korean Neuropsychiatric Association.


  • Bipolar disorder
  • Cohort study
  • Major depressive disorder
  • Mood disorder
  • Review

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


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