Abstract
We report two cases of interventional radiologists who had been exposed to radiation while performing fluoroscopically-guided interventional procedures (FGIPs), mainly transcatheter arterial chemoembolization, percutaneous catheter drainage, and percutaneous transhepatic biliary drainage procedures, for over 10 years. They had a unique multi-aberrant cell type with not only high numbers of dicentrics and/or centric rings but also excess acentric double minutes, similar to a rogue cell. As revealed in a self-administered questionnaire, they wore personal dosimeters and protective equipment at all times and used shielding devices during interventional fluoroscopy procedures. However, the exposed dose levels derived from cytogenetic dosimetry were much higher than the doses recorded on their personal dosimeters. A large number of unstable and stable chromosomal aberrations that were found in the peripheral blood lymphocytes of these interventional radiologists might be due to repeated and long-term exposure to ionizing radiation while performing FGIPs. Further investigations of chromosomal aberrations in interventional radiologists may improve the understanding of the long-term effects of radiation exposure on medical personnel.
Original language | English |
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Article number | 503234 |
Journal | Mutation Research - Genetic Toxicology and Environmental Mutagenesis |
Volume | 856-857 |
DOIs | |
Publication status | Published - 2020 Aug 1 |
Bibliographical note
Funding Information:This research was supported by the grants of the Korea Institute of Radiological and Medical Sciences, funded by Ministry of Science and ICT (No. 50445-2020), the Nuclear Safety and Security Commission (No. 1803014) and the Korea Ministry of Health and Welfare and Center for Disease Control and Prevention (No. 2017E3600600), Republic of Korea.
Funding Information:
This research was supported by the grants of the Korea Institute of Radiological and Medical Sciences , funded by Ministry of Science and ICT (No. 50445-2020 ), the Nuclear Safety and Security Commission (No. 1803014 ) and the Korea Ministry of Health and Welfare and Center for Disease Control and Prevention (No. 2017E3600600 ), Republic of Korea .
Publisher Copyright:
© 2020 The Authors
Keywords
- Dicentrics
- Dose monitoring
- Fluoroscopy procedures
- Occupational exposure
- Radiation protection
ASJC Scopus subject areas
- Genetics
- Health, Toxicology and Mutagenesis